Deubiquitylase USP52 Promotes Bladder Cancer Progression by Modulating Ferroptosis through Stabilizing SLC7A11/xCT

Deubiquitylase USP52 Promotes Bladder Cancer Progression by Modulating Ferroptosis through Stabilizing SLC7A11/xCT

Abstract Bladder cancer (BLCA) is a prevalent cancer with high case‐fatality rates and a substantial economic burden worldwide. Understanding its molecular underpinnings to guide clinical management is crucial. Ferroptosis, a recently described non‐apoptotic form of cell death, is initiated by the l...

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Main Authors: Jianmin Liu, Yongwen Luo, Siming Chen, Gang Wang, Wan Jin, Wenyu Jiang, Mingxing Li, Yejinpeng Wang, Jingtian Yu, Houyi Wei, Renjie Zhang, Fenfang Zhou, Lingao Ju, Yi Zhang, Yu Xiao, Kaiyu Qian, Xinghuan Wang
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:Advanced Science
Subjects:
bladder cancer
deubiquitylases
ferroptosis
SLC7A11/xCT
USP52
Online Access:https://doi.org/10.1002/advs.202403995
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https://doi.org/10.1002/advs.202403995

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