An Interesting Case of Bilateral Facial Palsy due to Granulomatosis with Polyangiitis
Granulomatosis with polyangiitis (formerly called Wegener’s granulomatosis) is a systemic autoimmune disease, which can lead to necrotizing vasculitis affecting small vessels and cause inflammation of blood vessels in the nose, sinuses, throat, lungs, and kidneys. In rare instances, it has shown inv...
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Format: | Article |
Language: | English |
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Wiley
2021-01-01
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Series: | Case Reports in Rheumatology |
Online Access: | http://dx.doi.org/10.1155/2021/9963564 |
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author | Rajish Sanjit Kumar Shil Jamal Ali Teir |
author_facet | Rajish Sanjit Kumar Shil Jamal Ali Teir |
author_sort | Rajish Sanjit Kumar Shil |
collection | DOAJ |
description | Granulomatosis with polyangiitis (formerly called Wegener’s granulomatosis) is a systemic autoimmune disease, which can lead to necrotizing vasculitis affecting small vessels and cause inflammation of blood vessels in the nose, sinuses, throat, lungs, and kidneys. In rare instances, it has shown involvement of the brain and cranial nerves as well. We are reporting a case of granulomatosis with polyangiitis, complicated by bilateral facial palsy due to lower motor neuron involvement of the facial nerve, which has responded well to immunosuppressive treatment, particularly rituximab. It is prudent to be vigilant in investigating patients with atypical presentation for systemic autoimmune diseases, as this approach would affect the patient morbidity and mortality with early initiation of treatment for the disease. |
format | Article |
id | doaj-art-e3fa33eb6dd44523ac0f5c86c5c70961 |
institution | Kabale University |
issn | 2090-6889 2090-6897 |
language | English |
publishDate | 2021-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Rheumatology |
spelling | doaj-art-e3fa33eb6dd44523ac0f5c86c5c709612025-02-03T05:45:20ZengWileyCase Reports in Rheumatology2090-68892090-68972021-01-01202110.1155/2021/99635649963564An Interesting Case of Bilateral Facial Palsy due to Granulomatosis with PolyangiitisRajish Sanjit Kumar Shil0Jamal Ali Teir1Department of Internal Medicine, Medical Institute, Al Ain Hospital, Al Ain, UAEDepartment of Rheumatology, Medical Institute, Al Ain Hospital, Sheikh Khalifa Hospital, Abu Dhabi, UAEGranulomatosis with polyangiitis (formerly called Wegener’s granulomatosis) is a systemic autoimmune disease, which can lead to necrotizing vasculitis affecting small vessels and cause inflammation of blood vessels in the nose, sinuses, throat, lungs, and kidneys. In rare instances, it has shown involvement of the brain and cranial nerves as well. We are reporting a case of granulomatosis with polyangiitis, complicated by bilateral facial palsy due to lower motor neuron involvement of the facial nerve, which has responded well to immunosuppressive treatment, particularly rituximab. It is prudent to be vigilant in investigating patients with atypical presentation for systemic autoimmune diseases, as this approach would affect the patient morbidity and mortality with early initiation of treatment for the disease.http://dx.doi.org/10.1155/2021/9963564 |
spellingShingle | Rajish Sanjit Kumar Shil Jamal Ali Teir An Interesting Case of Bilateral Facial Palsy due to Granulomatosis with Polyangiitis Case Reports in Rheumatology |
title | An Interesting Case of Bilateral Facial Palsy due to Granulomatosis with Polyangiitis |
title_full | An Interesting Case of Bilateral Facial Palsy due to Granulomatosis with Polyangiitis |
title_fullStr | An Interesting Case of Bilateral Facial Palsy due to Granulomatosis with Polyangiitis |
title_full_unstemmed | An Interesting Case of Bilateral Facial Palsy due to Granulomatosis with Polyangiitis |
title_short | An Interesting Case of Bilateral Facial Palsy due to Granulomatosis with Polyangiitis |
title_sort | interesting case of bilateral facial palsy due to granulomatosis with polyangiitis |
url | http://dx.doi.org/10.1155/2021/9963564 |
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