Sex and Age-Based Differences in Immune Responses to a Peptide Vaccine for Melanoma in Two Clinical Trials

Sex and Age-Based Differences in Immune Responses to a Peptide Vaccine for Melanoma in Two Clinical Trials

Objectives: Little is known about the impact of patient age and biological sex on immune responses to melanoma vaccines, especially CD4<sup>+</sup> T cell immune responses to peptides presented by Class II MHC molecules. Methods: We assessed the impact of age and sex on CD4+ T cell and a...

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Bibliographic Details
Main Authors: Serena M. Vilasi, Craig L. Slingluff
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Vaccines
Subjects:
melanoma vaccine
peptide vaccine
T cell response
patient sex
patient age
Online Access:https://www.mdpi.com/2076-393X/13/2/194
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