Improvement of depressive symptoms, after a suicide attempt, with dextromethorphan/bupropion combination treatment in a patient with treatment‐resistant depression and psychiatric comorbidities
Abstract We admitted a 42‐year‐old patient with severe treatment‐resistant depression and with psychiatric comorbidities. The patient attempted suicide 5 weeks after admission. Subsequently, we initiated dextromethorphan/bupropion based on prior evidence. As a result, the patient demonstrated an imp...
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| Format: | Article |
| Language: | English |
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Wiley
2023-03-01
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| Series: | Clinical Case Reports |
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| Online Access: | https://doi.org/10.1002/ccr3.7045 |
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| author | Bruno Pedraz‐Petrozzi Michael Deuschle Maria Gilles |
| author_facet | Bruno Pedraz‐Petrozzi Michael Deuschle Maria Gilles |
| author_sort | Bruno Pedraz‐Petrozzi |
| collection | DOAJ |
| description | Abstract We admitted a 42‐year‐old patient with severe treatment‐resistant depression and with psychiatric comorbidities. The patient attempted suicide 5 weeks after admission. Subsequently, we initiated dextromethorphan/bupropion based on prior evidence. As a result, the patient demonstrated an improvement in mood symptoms and a reduction in suicide risk, leading to her discharge. |
| format | Article |
| id | doaj-art-e3e7ef88683e4400a5173ffcd2426edb |
| institution | Kabale University |
| issn | 2050-0904 |
| language | English |
| publishDate | 2023-03-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical Case Reports |
| spelling | doaj-art-e3e7ef88683e4400a5173ffcd2426edb2025-08-20T03:47:23ZengWileyClinical Case Reports2050-09042023-03-01113n/an/a10.1002/ccr3.7045Improvement of depressive symptoms, after a suicide attempt, with dextromethorphan/bupropion combination treatment in a patient with treatment‐resistant depression and psychiatric comorbiditiesBruno Pedraz‐Petrozzi0Michael Deuschle1Maria Gilles2Department of Psychiatry and Psychotherapy, RG Stress, Central Institute of Mental Health, Medical Faculty Mannheim University of Heidelberg Mannheim GermanyDepartment of Psychiatry and Psychotherapy, RG Stress, Central Institute of Mental Health, Medical Faculty Mannheim University of Heidelberg Mannheim GermanyDepartment of Psychiatry and Psychotherapy, RG Stress, Central Institute of Mental Health, Medical Faculty Mannheim University of Heidelberg Mannheim GermanyAbstract We admitted a 42‐year‐old patient with severe treatment‐resistant depression and with psychiatric comorbidities. The patient attempted suicide 5 weeks after admission. Subsequently, we initiated dextromethorphan/bupropion based on prior evidence. As a result, the patient demonstrated an improvement in mood symptoms and a reduction in suicide risk, leading to her discharge.https://doi.org/10.1002/ccr3.7045bupropioncomorbiditydepressiondextromethorphansuicidal ideation |
| spellingShingle | Bruno Pedraz‐Petrozzi Michael Deuschle Maria Gilles Improvement of depressive symptoms, after a suicide attempt, with dextromethorphan/bupropion combination treatment in a patient with treatment‐resistant depression and psychiatric comorbidities Clinical Case Reports bupropion comorbidity depression dextromethorphan suicidal ideation |
| title | Improvement of depressive symptoms, after a suicide attempt, with dextromethorphan/bupropion combination treatment in a patient with treatment‐resistant depression and psychiatric comorbidities |
| title_full | Improvement of depressive symptoms, after a suicide attempt, with dextromethorphan/bupropion combination treatment in a patient with treatment‐resistant depression and psychiatric comorbidities |
| title_fullStr | Improvement of depressive symptoms, after a suicide attempt, with dextromethorphan/bupropion combination treatment in a patient with treatment‐resistant depression and psychiatric comorbidities |
| title_full_unstemmed | Improvement of depressive symptoms, after a suicide attempt, with dextromethorphan/bupropion combination treatment in a patient with treatment‐resistant depression and psychiatric comorbidities |
| title_short | Improvement of depressive symptoms, after a suicide attempt, with dextromethorphan/bupropion combination treatment in a patient with treatment‐resistant depression and psychiatric comorbidities |
| title_sort | improvement of depressive symptoms after a suicide attempt with dextromethorphan bupropion combination treatment in a patient with treatment resistant depression and psychiatric comorbidities |
| topic | bupropion comorbidity depression dextromethorphan suicidal ideation |
| url | https://doi.org/10.1002/ccr3.7045 |
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