Severe Thrombocytopenia Two Weeks Following Immunization with the Janssen Ad26.CoV2.S Vaccine
Immune thrombocytopenia (ITP) has been associated with immunizations with various proposed mechanisms, including overactivation of the immune system and production of antibodies against circulating platelets. ITP has also been associated with several viral infections, including HCV, HIV, and most re...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Case Reports in Hematology |
| Online Access: | http://dx.doi.org/10.1155/2022/7208401 |
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| _version_ | 1832554740048723968 |
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| author | Bana Antonios Markie Zimmer Emma Herrman Ramona Berghea |
| author_facet | Bana Antonios Markie Zimmer Emma Herrman Ramona Berghea |
| author_sort | Bana Antonios |
| collection | DOAJ |
| description | Immune thrombocytopenia (ITP) has been associated with immunizations with various proposed mechanisms, including overactivation of the immune system and production of antibodies against circulating platelets. ITP has also been associated with several viral infections, including HCV, HIV, and most recently, active SARS-CoV-2 infection. Here, we present a case of a 52-year-old male with no past medical history who sought evaluation with his primary care physician for upper and lower extremity ecchymosis of one week duration. Outpatient laboratory studies were notable for severe isolated thrombocytopenia with platelet count of 8 × 10^9/L. Interestingly, he received the Johnson and Johnson COVID-19 vaccine 16 days prior to his presentation. Clinical work up and laboratory investigations led to the diagnosis of ITP. |
| format | Article |
| id | doaj-art-e3e2fa57d1be40cbadb698cf3faa7f1a |
| institution | Kabale University |
| issn | 2090-6579 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Hematology |
| spelling | doaj-art-e3e2fa57d1be40cbadb698cf3faa7f1a2025-02-03T05:50:44ZengWileyCase Reports in Hematology2090-65792022-01-01202210.1155/2022/7208401Severe Thrombocytopenia Two Weeks Following Immunization with the Janssen Ad26.CoV2.S VaccineBana Antonios0Markie Zimmer1Emma Herrman2Ramona Berghea3Department of Internal MedicineDepartment of Internal MedicineDepartment of Internal MedicineDepartment of Internal MedicineImmune thrombocytopenia (ITP) has been associated with immunizations with various proposed mechanisms, including overactivation of the immune system and production of antibodies against circulating platelets. ITP has also been associated with several viral infections, including HCV, HIV, and most recently, active SARS-CoV-2 infection. Here, we present a case of a 52-year-old male with no past medical history who sought evaluation with his primary care physician for upper and lower extremity ecchymosis of one week duration. Outpatient laboratory studies were notable for severe isolated thrombocytopenia with platelet count of 8 × 10^9/L. Interestingly, he received the Johnson and Johnson COVID-19 vaccine 16 days prior to his presentation. Clinical work up and laboratory investigations led to the diagnosis of ITP.http://dx.doi.org/10.1155/2022/7208401 |
| spellingShingle | Bana Antonios Markie Zimmer Emma Herrman Ramona Berghea Severe Thrombocytopenia Two Weeks Following Immunization with the Janssen Ad26.CoV2.S Vaccine Case Reports in Hematology |
| title | Severe Thrombocytopenia Two Weeks Following Immunization with the Janssen Ad26.CoV2.S Vaccine |
| title_full | Severe Thrombocytopenia Two Weeks Following Immunization with the Janssen Ad26.CoV2.S Vaccine |
| title_fullStr | Severe Thrombocytopenia Two Weeks Following Immunization with the Janssen Ad26.CoV2.S Vaccine |
| title_full_unstemmed | Severe Thrombocytopenia Two Weeks Following Immunization with the Janssen Ad26.CoV2.S Vaccine |
| title_short | Severe Thrombocytopenia Two Weeks Following Immunization with the Janssen Ad26.CoV2.S Vaccine |
| title_sort | severe thrombocytopenia two weeks following immunization with the janssen ad26 cov2 s vaccine |
| url | http://dx.doi.org/10.1155/2022/7208401 |
| work_keys_str_mv | AT banaantonios severethrombocytopeniatwoweeksfollowingimmunizationwiththejanssenad26cov2svaccine AT markiezimmer severethrombocytopeniatwoweeksfollowingimmunizationwiththejanssenad26cov2svaccine AT emmaherrman severethrombocytopeniatwoweeksfollowingimmunizationwiththejanssenad26cov2svaccine AT ramonaberghea severethrombocytopeniatwoweeksfollowingimmunizationwiththejanssenad26cov2svaccine |