An mRNA Vaccine Expressing Blood-Stage Malaria Antigens Induces Complete Protection Against Lethal <i>Plasmodium yoelii</i>

An mRNA Vaccine Expressing Blood-Stage Malaria Antigens Induces Complete Protection Against Lethal <i>Plasmodium yoelii</i>

Background and Objectives: To evaluate the mRNA vaccine platform for blood-stage <i>Plasmodium</i> parasites, we completed a proof-of-concept study using the <i>P. yoelii</i> mouse model of malaria and two mRNA-based vaccines. Both encoded <i>Py</i>MSP1<sub>...

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Bibliographic Details
Main Authors:	Amy C. Ott, Patrick J. Loll, James M. Burns
Format:	Article
Language:	English
Published:	MDPI AG 2025-06-01
Series:	Vaccines
Subjects:	malaria <i>Plasmodium</i> <i>Plasmodium yoelii</i> vaccines mRNA blood-stage malaria
Online Access:	https://www.mdpi.com/2076-393X/13/7/702
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