An intradermal inoculation model of scrub typhus in Swiss CD-1 mice demonstrates more rapid dissemination of virulent strains of Orientia tsutsugamushi.

An intradermal inoculation model of scrub typhus in Swiss CD-1 mice demonstrates more rapid dissemination of virulent strains of Orientia tsutsugamushi.

Scrub typhus is an important endemic disease of the Asia-Pacific region caused by Orientia tsutsugamushi. To develop an effective vaccine to prevent scrub typhus infection, a better understanding of the initial host-pathogen interaction is needed. The objective of this study was to investigate early...

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Main Authors: Piyanate Sunyakumthorn, Daniel H Paris, Teik-Chye Chan, Margaret Jones, Alison Luce-Fedrow, Suchismita Chattopadhyay, Ju Jiang, Tippawan Anantatat, Gareth D H Turner, Nicholas P J Day, Allen L Richards
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0054570&type=printable
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