OPPORTUNITIES TO OPTIMIZE ANTIEPILEPTIC THERAPY WITH USE OF PHARMACOGENETIC BIOMARKERS
Pharmacogenetics allows to determine the cause of the ineffectiveness of drug therapy for certain groups of people who do not respond to treatment or exhibiting an inadequate response to a standard dose of the drug. Pharmacogenetic test can predict the speed and features of a metabolism of antiepile...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | Russian |
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IRBIS LLC
2016-05-01
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| Series: | Эпилепсия и пароксизмальные состояния |
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| Online Access: | https://www.epilepsia.su/jour/article/view/10 |
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| author | T. V. Dokukina M. V. Makhrov I. V. Gaidukevich A. A. Gilep T. S. Golubeva F. P. Khlebokazov N. N. Misyuk P. P. Korolevich |
| author_facet | T. V. Dokukina M. V. Makhrov I. V. Gaidukevich A. A. Gilep T. S. Golubeva F. P. Khlebokazov N. N. Misyuk P. P. Korolevich |
| author_sort | T. V. Dokukina |
| collection | DOAJ |
| description | Pharmacogenetics allows to determine the cause of the ineffectiveness of drug therapy for certain groups of people who do not respond to treatment or exhibiting an inadequate response to a standard dose of the drug. Pharmacogenetic test can predict the speed and features of a metabolism of antiepileptic drugs in patients with epilepsy, depending on the activity involved in their metabolism enzyme systems and conveyors, that allows to individualize drug therapy in epileptological practice, to avoid side effects. |
| format | Article |
| id | doaj-art-e3bc7a4e3b944c48bfdeefe3bf7a5293 |
| institution | DOAJ |
| issn | 2077-8333 2311-4088 |
| language | Russian |
| publishDate | 2016-05-01 |
| publisher | IRBIS LLC |
| record_format | Article |
| series | Эпилепсия и пароксизмальные состояния |
| spelling | doaj-art-e3bc7a4e3b944c48bfdeefe3bf7a52932025-08-20T02:58:56ZrusIRBIS LLCЭпилепсия и пароксизмальные состояния2077-83332311-40882016-05-017422289OPPORTUNITIES TO OPTIMIZE ANTIEPILEPTIC THERAPY WITH USE OF PHARMACOGENETIC BIOMARKERST. V. Dokukina0M. V. Makhrov1I. V. Gaidukevich2A. A. Gilep3T. S. Golubeva4F. P. Khlebokazov5N. N. Misyuk6P. P. Korolevich7Republican Scientific and Practical Center for Mental Health, MinskRepublican Scientific and Practical Center for Mental Health, MinskInstitute of Bioorganic Chemistry of the National Academy of Sciences of Belarus, MinskInstitute of Bioorganic Chemistry of the National Academy of Sciences of Belarus, MinskRepublican Scientific and Practical Center for Mental Health, MinskRepublican Scientific and Practical Center for Mental Health, MinskRepublican Scientific and Practical Center for Mental Health, MinskRepublican Scientific and Practical Center for Mental Health, MinskPharmacogenetics allows to determine the cause of the ineffectiveness of drug therapy for certain groups of people who do not respond to treatment or exhibiting an inadequate response to a standard dose of the drug. Pharmacogenetic test can predict the speed and features of a metabolism of antiepileptic drugs in patients with epilepsy, depending on the activity involved in their metabolism enzyme systems and conveyors, that allows to individualize drug therapy in epileptological practice, to avoid side effects.https://www.epilepsia.su/jour/article/view/10pharmacogeneticsanticonvulsantsepilepsydrug-resistancednagenotyping |
| spellingShingle | T. V. Dokukina M. V. Makhrov I. V. Gaidukevich A. A. Gilep T. S. Golubeva F. P. Khlebokazov N. N. Misyuk P. P. Korolevich OPPORTUNITIES TO OPTIMIZE ANTIEPILEPTIC THERAPY WITH USE OF PHARMACOGENETIC BIOMARKERS Эпилепсия и пароксизмальные состояния pharmacogenetics anticonvulsants epilepsy drug-resistance dna genotyping |
| title | OPPORTUNITIES TO OPTIMIZE ANTIEPILEPTIC THERAPY WITH USE OF PHARMACOGENETIC BIOMARKERS |
| title_full | OPPORTUNITIES TO OPTIMIZE ANTIEPILEPTIC THERAPY WITH USE OF PHARMACOGENETIC BIOMARKERS |
| title_fullStr | OPPORTUNITIES TO OPTIMIZE ANTIEPILEPTIC THERAPY WITH USE OF PHARMACOGENETIC BIOMARKERS |
| title_full_unstemmed | OPPORTUNITIES TO OPTIMIZE ANTIEPILEPTIC THERAPY WITH USE OF PHARMACOGENETIC BIOMARKERS |
| title_short | OPPORTUNITIES TO OPTIMIZE ANTIEPILEPTIC THERAPY WITH USE OF PHARMACOGENETIC BIOMARKERS |
| title_sort | opportunities to optimize antiepileptic therapy with use of pharmacogenetic biomarkers |
| topic | pharmacogenetics anticonvulsants epilepsy drug-resistance dna genotyping |
| url | https://www.epilepsia.su/jour/article/view/10 |
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