Dedifferentiated liposarcoma of the anterior mediastinum: An uncommon case presentation and complex diagnosis
Mediastinal liposarcoma are rare occurrences of liposarcomas, arising from mesenchymal fat cells. They have several histological subtypes including well-differentiated, dedifferentiated, myxoid and pleomorphic. They often present with nonspecific symptoms of mass effect on nearby structures. Surgica...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-06-01
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| Series: | Radiology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043325002444 |
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| Summary: | Mediastinal liposarcoma are rare occurrences of liposarcomas, arising from mesenchymal fat cells. They have several histological subtypes including well-differentiated, dedifferentiated, myxoid and pleomorphic. They often present with nonspecific symptoms of mass effect on nearby structures. Surgical resection is the mainstay of treatment, but high recurrence rate remains a challenge. We present the case of a 70-year-old male with a large dedifferentiated anterior mediastinal liposarcoma presenting with compressive symptoms. Coordinated efforts from radiology, histopathology and surgical teams are required for timely and accurate diagnosis and an optimized course of treatment. |
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| ISSN: | 1930-0433 |