Recurrent Adult Sacrococcygeal Teratoma Developing Adenocarcinoma: A Case Report and Review of Literatures
Sacrococcygeal teratomas (SCT) are most commonly seen in infants and children but are rare in adults. Most adult SCT are benign and mature with a minority of tumors having immature components or overt malignancy. Here, we report a 65-year-old female with a SCT developing adenocarcinoma. The patient...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Case Reports in Pathology |
| Online Access: | http://dx.doi.org/10.1155/2021/5045250 |
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| author | Shengjie Cui Jing Han Binny Khandakar Barak Friedman Domingo Nunez Gabriel A. Sara Gabriel S. Levi |
| author_facet | Shengjie Cui Jing Han Binny Khandakar Barak Friedman Domingo Nunez Gabriel A. Sara Gabriel S. Levi |
| author_sort | Shengjie Cui |
| collection | DOAJ |
| description | Sacrococcygeal teratomas (SCT) are most commonly seen in infants and children but are rare in adults. Most adult SCT are benign and mature with a minority of tumors having immature components or overt malignancy. Here, we report a 65-year-old female with a SCT developing adenocarcinoma. The patient was diagnosed with benign sacrococcygeal cystic teratoma on her initial hospital visit and was treated with surgical resection. She was followed up postoperatively and was noted to have a markedly elevated CA 19-9 level 13 months after the surgery. Radiological and clinical examination revealed thickening of the perirectal soft tissues, located near the inferior portion of her previous incision site. Histological evaluation of the lesion showed invasive, moderately differentiated adenocarcinoma. Immunohistochemical staining results were suggestive, but not diagnostic, of anal gland adenocarcinoma. This case report expands the knowledge regarding an adenocarcinoma arising from a previously benign, adult SCT. |
| format | Article |
| id | doaj-art-e3a5634ba4b94d75823ab3873e0cb1be |
| institution | Kabale University |
| issn | 2090-679X |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pathology |
| spelling | doaj-art-e3a5634ba4b94d75823ab3873e0cb1be2025-02-03T01:03:42ZengWileyCase Reports in Pathology2090-679X2021-01-01202110.1155/2021/5045250Recurrent Adult Sacrococcygeal Teratoma Developing Adenocarcinoma: A Case Report and Review of LiteraturesShengjie Cui0Jing Han1Binny Khandakar2Barak Friedman3Domingo Nunez4Gabriel A. Sara5Gabriel S. Levi6The Department of PathologyThe Department of PathologyThe Department of PathologyDepartment of Diagnostic, Molecular and Interventional RadiologyThe Department of SurgeryThe Department of MedicineThe Department of PathologySacrococcygeal teratomas (SCT) are most commonly seen in infants and children but are rare in adults. Most adult SCT are benign and mature with a minority of tumors having immature components or overt malignancy. Here, we report a 65-year-old female with a SCT developing adenocarcinoma. The patient was diagnosed with benign sacrococcygeal cystic teratoma on her initial hospital visit and was treated with surgical resection. She was followed up postoperatively and was noted to have a markedly elevated CA 19-9 level 13 months after the surgery. Radiological and clinical examination revealed thickening of the perirectal soft tissues, located near the inferior portion of her previous incision site. Histological evaluation of the lesion showed invasive, moderately differentiated adenocarcinoma. Immunohistochemical staining results were suggestive, but not diagnostic, of anal gland adenocarcinoma. This case report expands the knowledge regarding an adenocarcinoma arising from a previously benign, adult SCT.http://dx.doi.org/10.1155/2021/5045250 |
| spellingShingle | Shengjie Cui Jing Han Binny Khandakar Barak Friedman Domingo Nunez Gabriel A. Sara Gabriel S. Levi Recurrent Adult Sacrococcygeal Teratoma Developing Adenocarcinoma: A Case Report and Review of Literatures Case Reports in Pathology |
| title | Recurrent Adult Sacrococcygeal Teratoma Developing Adenocarcinoma: A Case Report and Review of Literatures |
| title_full | Recurrent Adult Sacrococcygeal Teratoma Developing Adenocarcinoma: A Case Report and Review of Literatures |
| title_fullStr | Recurrent Adult Sacrococcygeal Teratoma Developing Adenocarcinoma: A Case Report and Review of Literatures |
| title_full_unstemmed | Recurrent Adult Sacrococcygeal Teratoma Developing Adenocarcinoma: A Case Report and Review of Literatures |
| title_short | Recurrent Adult Sacrococcygeal Teratoma Developing Adenocarcinoma: A Case Report and Review of Literatures |
| title_sort | recurrent adult sacrococcygeal teratoma developing adenocarcinoma a case report and review of literatures |
| url | http://dx.doi.org/10.1155/2021/5045250 |
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