TNF-α Dysregulation in Asthma: Relationship to Ongoing Corticosteroid Therapy
BACKGROUND: Tumour necrosis factor-alpha (TNF-α) is a major proinflammatory cytokine that is thought to be important in the pathogenesis of asthma. However, alterations in systemic regulation of this cytokine in asthma have not been examined in the context of corticosteroid therapy.
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Format: | Article |
Language: | English |
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Wiley
2000-01-01
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Series: | Canadian Respiratory Journal |
Online Access: | http://dx.doi.org/10.1155/2000/565386 |
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author | Susan Waserman Jerry Dolovich Mary Conway Jean S Marshall |
author_facet | Susan Waserman Jerry Dolovich Mary Conway Jean S Marshall |
author_sort | Susan Waserman |
collection | DOAJ |
description | BACKGROUND: Tumour necrosis factor-alpha (TNF-α) is a major proinflammatory cytokine that is thought to be important in the pathogenesis of asthma. However, alterations in systemic regulation of this cytokine in asthma have not been examined in the context of corticosteroid therapy. |
format | Article |
id | doaj-art-e3935df7959b4f4799124cdefbed13de |
institution | Kabale University |
issn | 1198-2241 |
language | English |
publishDate | 2000-01-01 |
publisher | Wiley |
record_format | Article |
series | Canadian Respiratory Journal |
spelling | doaj-art-e3935df7959b4f4799124cdefbed13de2025-02-03T05:49:33ZengWileyCanadian Respiratory Journal1198-22412000-01-017322923710.1155/2000/565386TNF-α Dysregulation in Asthma: Relationship to Ongoing Corticosteroid TherapySusan Waserman0Jerry Dolovich1Mary ConwayJean S Marshall2Department of Medicine, McMaster University Medical Centre and McMaster University, Hamilton, Ontario, CanadaDepartment of Pediatrics, McMaster University Medical Centre and McMaster University, Hamilton, Ontario, CanadaDepartment of Microbiology and Immunology, Dalhousie University, Halifax, Nova Scotia, CanadaBACKGROUND: Tumour necrosis factor-alpha (TNF-α) is a major proinflammatory cytokine that is thought to be important in the pathogenesis of asthma. However, alterations in systemic regulation of this cytokine in asthma have not been examined in the context of corticosteroid therapy.http://dx.doi.org/10.1155/2000/565386 |
spellingShingle | Susan Waserman Jerry Dolovich Mary Conway Jean S Marshall TNF-α Dysregulation in Asthma: Relationship to Ongoing Corticosteroid Therapy Canadian Respiratory Journal |
title | TNF-α Dysregulation in Asthma: Relationship to Ongoing Corticosteroid Therapy |
title_full | TNF-α Dysregulation in Asthma: Relationship to Ongoing Corticosteroid Therapy |
title_fullStr | TNF-α Dysregulation in Asthma: Relationship to Ongoing Corticosteroid Therapy |
title_full_unstemmed | TNF-α Dysregulation in Asthma: Relationship to Ongoing Corticosteroid Therapy |
title_short | TNF-α Dysregulation in Asthma: Relationship to Ongoing Corticosteroid Therapy |
title_sort | tnf α dysregulation in asthma relationship to ongoing corticosteroid therapy |
url | http://dx.doi.org/10.1155/2000/565386 |
work_keys_str_mv | AT susanwaserman tnfadysregulationinasthmarelationshiptoongoingcorticosteroidtherapy AT jerrydolovich tnfadysregulationinasthmarelationshiptoongoingcorticosteroidtherapy AT maryconway tnfadysregulationinasthmarelationshiptoongoingcorticosteroidtherapy AT jeansmarshall tnfadysregulationinasthmarelationshiptoongoingcorticosteroidtherapy |