TNF-α Dysregulation in Asthma: Relationship to Ongoing Corticosteroid Therapy

BACKGROUND: Tumour necrosis factor-alpha (TNF-α) is a major proinflammatory cytokine that is thought to be important in the pathogenesis of asthma. However, alterations in systemic regulation of this cytokine in asthma have not been examined in the context of corticosteroid therapy.

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Bibliographic Details
Main Authors: Susan Waserman, Jerry Dolovich, Mary Conway, Jean S Marshall
Format: Article
Language:English
Published: Wiley 2000-01-01
Series:Canadian Respiratory Journal
Online Access:http://dx.doi.org/10.1155/2000/565386
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author Susan Waserman
Jerry Dolovich
Mary Conway
Jean S Marshall
author_facet Susan Waserman
Jerry Dolovich
Mary Conway
Jean S Marshall
author_sort Susan Waserman
collection DOAJ
description BACKGROUND: Tumour necrosis factor-alpha (TNF-α) is a major proinflammatory cytokine that is thought to be important in the pathogenesis of asthma. However, alterations in systemic regulation of this cytokine in asthma have not been examined in the context of corticosteroid therapy.
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institution Kabale University
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publishDate 2000-01-01
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series Canadian Respiratory Journal
spelling doaj-art-e3935df7959b4f4799124cdefbed13de2025-02-03T05:49:33ZengWileyCanadian Respiratory Journal1198-22412000-01-017322923710.1155/2000/565386TNF-α Dysregulation in Asthma: Relationship to Ongoing Corticosteroid TherapySusan Waserman0Jerry Dolovich1Mary ConwayJean S Marshall2Department of Medicine, McMaster University Medical Centre and McMaster University, Hamilton, Ontario, CanadaDepartment of Pediatrics, McMaster University Medical Centre and McMaster University, Hamilton, Ontario, CanadaDepartment of Microbiology and Immunology, Dalhousie University, Halifax, Nova Scotia, CanadaBACKGROUND: Tumour necrosis factor-alpha (TNF-α) is a major proinflammatory cytokine that is thought to be important in the pathogenesis of asthma. However, alterations in systemic regulation of this cytokine in asthma have not been examined in the context of corticosteroid therapy.http://dx.doi.org/10.1155/2000/565386
spellingShingle Susan Waserman
Jerry Dolovich
Mary Conway
Jean S Marshall
TNF-α Dysregulation in Asthma: Relationship to Ongoing Corticosteroid Therapy
Canadian Respiratory Journal
title TNF-α Dysregulation in Asthma: Relationship to Ongoing Corticosteroid Therapy
title_full TNF-α Dysregulation in Asthma: Relationship to Ongoing Corticosteroid Therapy
title_fullStr TNF-α Dysregulation in Asthma: Relationship to Ongoing Corticosteroid Therapy
title_full_unstemmed TNF-α Dysregulation in Asthma: Relationship to Ongoing Corticosteroid Therapy
title_short TNF-α Dysregulation in Asthma: Relationship to Ongoing Corticosteroid Therapy
title_sort tnf α dysregulation in asthma relationship to ongoing corticosteroid therapy
url http://dx.doi.org/10.1155/2000/565386
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AT jerrydolovich tnfadysregulationinasthmarelationshiptoongoingcorticosteroidtherapy
AT maryconway tnfadysregulationinasthmarelationshiptoongoingcorticosteroidtherapy
AT jeansmarshall tnfadysregulationinasthmarelationshiptoongoingcorticosteroidtherapy