Bladder Leiomyoma with Synchronous Solitary Fibrous Tumor of the Pleura
Bladder leiomyomas (BLs) are extremely rare benign tumors of mesenchymal origin. The exact pathophysiological mechanisms that lead to their appearance remain unclear including hormonal disorders, chromosomal abnormalities, and fetal remnants in the bladder. They usually remain asymptomatic for a lon...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Case Reports in Urology |
| Online Access: | http://dx.doi.org/10.1155/2020/3717506 |
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| author | Charalampos Mavridis George Georgiadis Eleni D. Lagoudaki Iordanis Skamagkas Ioannis Heretis Anastasios V. Koutsopoulos Charalampos Mamoulakis |
| author_facet | Charalampos Mavridis George Georgiadis Eleni D. Lagoudaki Iordanis Skamagkas Ioannis Heretis Anastasios V. Koutsopoulos Charalampos Mamoulakis |
| author_sort | Charalampos Mavridis |
| collection | DOAJ |
| description | Bladder leiomyomas (BLs) are extremely rare benign tumors of mesenchymal origin. The exact pathophysiological mechanisms that lead to their appearance remain unclear including hormonal disorders, chromosomal abnormalities, and fetal remnants in the bladder. They usually remain asymptomatic for a long period of time. Solitary fibrous tumors (SFTs) are also rare neoplasms of mesenchymal origin with malignant potential usually affecting the pleura. The pathogenesis of SFTs remains unclear. We report the case of a 28-year-old male presenting with SFT of the pleura and synchronous BL. The patient presented with persistent cough as a sole symptom. Computed tomography (CT) of the thorax revealed a pleural mass, which was surgically removed and proved to be a SFT. At an early follow-up, abdominal CT scan revealed a bladder wall mass that proved to be a BL. This is the first report of BL with synchronous SFT of the pleura. Synchronous BLs and SFTs may be incidental, but the coexistence of two mesenchymal tumors at different sites, in a young patient, may raise the suspicion of a new clinical syndrome that warrants further investigation. |
| format | Article |
| id | doaj-art-e37b76e784154436a387da00b620f06d |
| institution | Kabale University |
| issn | 2090-696X 2090-6978 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Urology |
| spelling | doaj-art-e37b76e784154436a387da00b620f06d2025-02-03T00:59:43ZengWileyCase Reports in Urology2090-696X2090-69782020-01-01202010.1155/2020/37175063717506Bladder Leiomyoma with Synchronous Solitary Fibrous Tumor of the PleuraCharalampos Mavridis0George Georgiadis1Eleni D. Lagoudaki2Iordanis Skamagkas3Ioannis Heretis4Anastasios V. Koutsopoulos5Charalampos Mamoulakis6Department of Urology, University General Hospital of Heraklion, University of Crete, Medical School, Heraklion, Crete, GreeceDepartment of Urology, University General Hospital of Heraklion, University of Crete, Medical School, Heraklion, Crete, GreeceDepartment of Pathology, University General Hospital of Heraklion, University of Crete, Medical School, Heraklion, Crete, GreeceDepartment of Urology, University General Hospital of Heraklion, University of Crete, Medical School, Heraklion, Crete, GreeceDepartment of Urology, University General Hospital of Heraklion, University of Crete, Medical School, Heraklion, Crete, GreeceDepartment of Pathology, University General Hospital of Heraklion, University of Crete, Medical School, Heraklion, Crete, GreeceDepartment of Urology, University General Hospital of Heraklion, University of Crete, Medical School, Heraklion, Crete, GreeceBladder leiomyomas (BLs) are extremely rare benign tumors of mesenchymal origin. The exact pathophysiological mechanisms that lead to their appearance remain unclear including hormonal disorders, chromosomal abnormalities, and fetal remnants in the bladder. They usually remain asymptomatic for a long period of time. Solitary fibrous tumors (SFTs) are also rare neoplasms of mesenchymal origin with malignant potential usually affecting the pleura. The pathogenesis of SFTs remains unclear. We report the case of a 28-year-old male presenting with SFT of the pleura and synchronous BL. The patient presented with persistent cough as a sole symptom. Computed tomography (CT) of the thorax revealed a pleural mass, which was surgically removed and proved to be a SFT. At an early follow-up, abdominal CT scan revealed a bladder wall mass that proved to be a BL. This is the first report of BL with synchronous SFT of the pleura. Synchronous BLs and SFTs may be incidental, but the coexistence of two mesenchymal tumors at different sites, in a young patient, may raise the suspicion of a new clinical syndrome that warrants further investigation.http://dx.doi.org/10.1155/2020/3717506 |
| spellingShingle | Charalampos Mavridis George Georgiadis Eleni D. Lagoudaki Iordanis Skamagkas Ioannis Heretis Anastasios V. Koutsopoulos Charalampos Mamoulakis Bladder Leiomyoma with Synchronous Solitary Fibrous Tumor of the Pleura Case Reports in Urology |
| title | Bladder Leiomyoma with Synchronous Solitary Fibrous Tumor of the Pleura |
| title_full | Bladder Leiomyoma with Synchronous Solitary Fibrous Tumor of the Pleura |
| title_fullStr | Bladder Leiomyoma with Synchronous Solitary Fibrous Tumor of the Pleura |
| title_full_unstemmed | Bladder Leiomyoma with Synchronous Solitary Fibrous Tumor of the Pleura |
| title_short | Bladder Leiomyoma with Synchronous Solitary Fibrous Tumor of the Pleura |
| title_sort | bladder leiomyoma with synchronous solitary fibrous tumor of the pleura |
| url | http://dx.doi.org/10.1155/2020/3717506 |
| work_keys_str_mv | AT charalamposmavridis bladderleiomyomawithsynchronoussolitaryfibroustumorofthepleura AT georgegeorgiadis bladderleiomyomawithsynchronoussolitaryfibroustumorofthepleura AT elenidlagoudaki bladderleiomyomawithsynchronoussolitaryfibroustumorofthepleura AT iordanisskamagkas bladderleiomyomawithsynchronoussolitaryfibroustumorofthepleura AT ioannisheretis bladderleiomyomawithsynchronoussolitaryfibroustumorofthepleura AT anastasiosvkoutsopoulos bladderleiomyomawithsynchronoussolitaryfibroustumorofthepleura AT charalamposmamoulakis bladderleiomyomawithsynchronoussolitaryfibroustumorofthepleura |