Management Challenges in a Child with Chronic Hyponatremia: Use of V2 Receptor Antagonist
Chronic hyponatremia is very rare in children and is often seen in the setting of congestive heart failure or liver failure in adults. Here, we report an 8-year-old child with hypothalamic glioma who presented with severe hyponatremia. Initial management consisted of fluid restriction. This was very...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Case Reports in Pediatrics |
| Online Access: | http://dx.doi.org/10.1155/2017/3757423 |
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| author | Sowmya Krishnan Swapna Deshpande Ashwini Mallappa Gunda Divya Pascale Lane Anu Vishwanath Rene Y. McNall-Knapp |
| author_facet | Sowmya Krishnan Swapna Deshpande Ashwini Mallappa Gunda Divya Pascale Lane Anu Vishwanath Rene Y. McNall-Knapp |
| author_sort | Sowmya Krishnan |
| collection | DOAJ |
| description | Chronic hyponatremia is very rare in children and is often seen in the setting of congestive heart failure or liver failure in adults. Here, we report an 8-year-old child with hypothalamic glioma who presented with severe hyponatremia. Initial management consisted of fluid restriction. This was very difficult for the child to follow and the child developed bizarre drinking habits requiring intervention from child psychiatry. So therapy was initiated with low dose V2 receptor antagonist under close inpatient monitoring. While initial response was reassuring, her sodium levels tended to drift down with longer duration of treatment requiring us to increase the dose frequently. Her response to therapy and her stable clinical situation off therapy suggest that she may have reset osmostat. |
| format | Article |
| id | doaj-art-e35c51296dda46769a53ac9ebcd8d2e9 |
| institution | OA Journals |
| issn | 2090-6803 2090-6811 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pediatrics |
| spelling | doaj-art-e35c51296dda46769a53ac9ebcd8d2e92025-08-20T02:21:24ZengWileyCase Reports in Pediatrics2090-68032090-68112017-01-01201710.1155/2017/37574233757423Management Challenges in a Child with Chronic Hyponatremia: Use of V2 Receptor AntagonistSowmya Krishnan0Swapna Deshpande1Ashwini Mallappa2Gunda Divya3Pascale Lane4Anu Vishwanath5Rene Y. McNall-Knapp6Department of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USADepartment of Psychiatry, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USADepartment of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USADepartment of Radiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USADepartment of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USADepartment of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USADepartment of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USAChronic hyponatremia is very rare in children and is often seen in the setting of congestive heart failure or liver failure in adults. Here, we report an 8-year-old child with hypothalamic glioma who presented with severe hyponatremia. Initial management consisted of fluid restriction. This was very difficult for the child to follow and the child developed bizarre drinking habits requiring intervention from child psychiatry. So therapy was initiated with low dose V2 receptor antagonist under close inpatient monitoring. While initial response was reassuring, her sodium levels tended to drift down with longer duration of treatment requiring us to increase the dose frequently. Her response to therapy and her stable clinical situation off therapy suggest that she may have reset osmostat.http://dx.doi.org/10.1155/2017/3757423 |
| spellingShingle | Sowmya Krishnan Swapna Deshpande Ashwini Mallappa Gunda Divya Pascale Lane Anu Vishwanath Rene Y. McNall-Knapp Management Challenges in a Child with Chronic Hyponatremia: Use of V2 Receptor Antagonist Case Reports in Pediatrics |
| title | Management Challenges in a Child with Chronic Hyponatremia: Use of V2 Receptor Antagonist |
| title_full | Management Challenges in a Child with Chronic Hyponatremia: Use of V2 Receptor Antagonist |
| title_fullStr | Management Challenges in a Child with Chronic Hyponatremia: Use of V2 Receptor Antagonist |
| title_full_unstemmed | Management Challenges in a Child with Chronic Hyponatremia: Use of V2 Receptor Antagonist |
| title_short | Management Challenges in a Child with Chronic Hyponatremia: Use of V2 Receptor Antagonist |
| title_sort | management challenges in a child with chronic hyponatremia use of v2 receptor antagonist |
| url | http://dx.doi.org/10.1155/2017/3757423 |
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