The Impact of <i>Lactobacillus reuteri</i> on Oral and Systemic Health: A Comprehensive Review of Recent Research

Oral diseases, particularly dental caries and periodontal disease, pose significant global health challenges. The imbalance of the oral microbiota plays a key role in the occurrence of these diseases, prompting researchers to seek new strategies to restore oral ecological balance. <i>Lactobaci...

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Bibliographic Details
Main Authors: Zihui Liu, Qing Cao, Wenqing Wang, Bowen Wang, Yilun Yang, Cory J. Xian, Tiejun Li, Yuankun Zhai
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Microorganisms
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Online Access:https://www.mdpi.com/2076-2607/13/1/45
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Summary:Oral diseases, particularly dental caries and periodontal disease, pose significant global health challenges. The imbalance of the oral microbiota plays a key role in the occurrence of these diseases, prompting researchers to seek new strategies to restore oral ecological balance. <i>Lactobacillus reuteri</i> is a Gram-positive rod-shaped bacterium that exists in various body parts of humans, including the gastrointestinal tract, urinary tract, skin, and so on. This species has a potentially positive impact on oral health and plays an important role in maintaining systemic health. Recent studies have explored the application of <i>Lactobacillus reuteri</i> in the prevention and treatment of oral diseases, and its impact on systemic health has also been preliminarily revealed. The current review summarizes the role of <i>Lactobacillus reuteri</i> in oral health and systemic health and outlines its potential applications in the future. <i>Lactobacillus reuteri</i> has shown promising prospects in treating non-communicable biofilm-dependent oral diseases, but its mechanism of action and efficacy still need further research. In addition, <i>Lactobacillus reuteri</i> has also displayed some potential benefits in promoting overall health. Future research should focus on revealing the specific pathways of action of <i>Lactobacillus reuteri</i>, screening for the most beneficial strains, determining the most effective drug delivery strategies, developing oral and systemic health products based on <i>Lactobacillus reuteri</i>, and ensuring their safety in clinical applications.
ISSN:2076-2607