Pilus-mediated co-aggregation with Lactobacillus crispatus increases meningococcal susceptibility to antimicrobial agents by interfering with microcolony formation

Abstract Background Neisseria meningitidis asymptomatically colonizes the nasopharyngeal mucosa, but occasionally, the bacteria disseminate to cause sepsis and meningitis. In the epithelial cell layer, the pathogen co-colonizes with other resident inhabitants, such as Lactobacillus species that are...

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Bibliographic Details
Main Authors: Kenny Lidberg, Sarah Pilheden, Samuddi Nawarathne, Katharina Rauscher, Ann-Beth Jonsson
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Microbiology
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Online Access:https://doi.org/10.1186/s12866-025-04201-2
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