Use of Next Generation Sequencing and Synergy Susceptibility Testing in Diagnosis and Treatment of Carbapenem-Resistant Klebsiella pneumoniae Blood Stream Infection
Early diagnosis and appropriate treatment for carbapenem-resistant Klebsiella pneumoniae (CR-Kp) infection is a big challenge for clinicians due to its high mortality. Every effort has been made to improve its clinical outcomes. However, treatment according to synergy susceptibility testing has neve...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2018-01-01
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| Series: | Case Reports in Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2018/3295605 |
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| _version_ | 1832566649790660608 |
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| author | Yuetian Yu Fupin Hu Cheng Zhu Erzhen Chen Liangjing Lu Yuan Gao |
| author_facet | Yuetian Yu Fupin Hu Cheng Zhu Erzhen Chen Liangjing Lu Yuan Gao |
| author_sort | Yuetian Yu |
| collection | DOAJ |
| description | Early diagnosis and appropriate treatment for carbapenem-resistant Klebsiella pneumoniae (CR-Kp) infection is a big challenge for clinicians due to its high mortality. Every effort has been made to improve its clinical outcomes. However, treatment according to synergy susceptibility testing has never been reported in the literature. We reported a 29-year-old systemic lupus erythematosus female with CR-Kp blood stream infection. We highlighted the identification by next generation sequencing and treatment according to synergy susceptibility testing in the case. |
| format | Article |
| id | doaj-art-e3236c4ce19d497f817d0814bf2e1bb5 |
| institution | Kabale University |
| issn | 2090-6625 2090-6633 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Infectious Diseases |
| spelling | doaj-art-e3236c4ce19d497f817d0814bf2e1bb52025-02-03T01:03:38ZengWileyCase Reports in Infectious Diseases2090-66252090-66332018-01-01201810.1155/2018/32956053295605Use of Next Generation Sequencing and Synergy Susceptibility Testing in Diagnosis and Treatment of Carbapenem-Resistant Klebsiella pneumoniae Blood Stream InfectionYuetian Yu0Fupin Hu1Cheng Zhu2Erzhen Chen3Liangjing Lu4Yuan Gao5Department of Critical Care Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200001, ChinaInstitute of Antibiotics, Huashan Hospital, Fudan University, Shanghai 200040, ChinaDepartment of Emergency Medicine, Rui Jin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200025, ChinaDepartment of Emergency Medicine, Rui Jin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200025, ChinaDepartment of Rheumatology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200001, ChinaDepartment of Critical Care Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200001, ChinaEarly diagnosis and appropriate treatment for carbapenem-resistant Klebsiella pneumoniae (CR-Kp) infection is a big challenge for clinicians due to its high mortality. Every effort has been made to improve its clinical outcomes. However, treatment according to synergy susceptibility testing has never been reported in the literature. We reported a 29-year-old systemic lupus erythematosus female with CR-Kp blood stream infection. We highlighted the identification by next generation sequencing and treatment according to synergy susceptibility testing in the case.http://dx.doi.org/10.1155/2018/3295605 |
| spellingShingle | Yuetian Yu Fupin Hu Cheng Zhu Erzhen Chen Liangjing Lu Yuan Gao Use of Next Generation Sequencing and Synergy Susceptibility Testing in Diagnosis and Treatment of Carbapenem-Resistant Klebsiella pneumoniae Blood Stream Infection Case Reports in Infectious Diseases |
| title | Use of Next Generation Sequencing and Synergy Susceptibility Testing in Diagnosis and Treatment of Carbapenem-Resistant Klebsiella pneumoniae Blood Stream Infection |
| title_full | Use of Next Generation Sequencing and Synergy Susceptibility Testing in Diagnosis and Treatment of Carbapenem-Resistant Klebsiella pneumoniae Blood Stream Infection |
| title_fullStr | Use of Next Generation Sequencing and Synergy Susceptibility Testing in Diagnosis and Treatment of Carbapenem-Resistant Klebsiella pneumoniae Blood Stream Infection |
| title_full_unstemmed | Use of Next Generation Sequencing and Synergy Susceptibility Testing in Diagnosis and Treatment of Carbapenem-Resistant Klebsiella pneumoniae Blood Stream Infection |
| title_short | Use of Next Generation Sequencing and Synergy Susceptibility Testing in Diagnosis and Treatment of Carbapenem-Resistant Klebsiella pneumoniae Blood Stream Infection |
| title_sort | use of next generation sequencing and synergy susceptibility testing in diagnosis and treatment of carbapenem resistant klebsiella pneumoniae blood stream infection |
| url | http://dx.doi.org/10.1155/2018/3295605 |
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