Long-Term Outcomes of Caustic Esophageal Stricture with Endoscopic Balloon Dilatation in Chinese Children
Caustic esophageal stricture (CES) in children still occurs frequently in developing countries. We aimed to evaluate the long-term outcomes of endoscopic balloon dilatation (EBD) in treating CES in children and the influencing factors associated with outcome. We retrospectively reviewed the data of...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2018/8352756 |
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| author | Lan-Lan Geng Cui-Ping Liang Pei-Yu Chen Qiang Wu Min Yang Hui-Wen Li Zhao-Hui Xu Lu Ren Hong-Li Wang Shunxian Cheng Wan-Fu Xu Yang Chen Chao Zhang Li-Ying Liu Ding-You Li Si-Tang Gong |
| author_facet | Lan-Lan Geng Cui-Ping Liang Pei-Yu Chen Qiang Wu Min Yang Hui-Wen Li Zhao-Hui Xu Lu Ren Hong-Li Wang Shunxian Cheng Wan-Fu Xu Yang Chen Chao Zhang Li-Ying Liu Ding-You Li Si-Tang Gong |
| author_sort | Lan-Lan Geng |
| collection | DOAJ |
| description | Caustic esophageal stricture (CES) in children still occurs frequently in developing countries. We aimed to evaluate the long-term outcomes of endoscopic balloon dilatation (EBD) in treating CES in children and the influencing factors associated with outcome. We retrospectively reviewed the data of all patients who had a diagnosis of CES and underwent EBD from August 1, 2005, to December 31, 2014. The primary outcome was EBD success, which was defined as the maintenance of dysphagia-free status for at least 12 months after the last EBD. The secondary outcome was to analyze influencing factors associated with EBD success. Forty-three patients were included for analysis (29 males; mean age at first dilatation 44 months with range 121 months). 26 (60.5%) patients had long segment (>2 cm) stricture. A total of 168 EBD procedures were performed. Twenty-six (60.5%) patients were considered EBD success. Seventeen (39.5%) patients failed EBD and required stent placement and/or surgery. Patients in the EBD success group had significantly shorter stricture segments when compared to the EBD failure group (t=2.398, P=0.018, OR=3.206, 95% OR: 1.228–8.371). Seven (4.4%) esophageal perforations occurred in 6 patients after EBD. Stents were placed in 5 patients, and gastric tube esophagoplasty was performed in 14 patients. In conclusion, 26 (60.5%) of 43 children with CES had EBD success. Length of stricture was the main influencing factor associated with EBD treatment outcome. |
| format | Article |
| id | doaj-art-e2fa1b54ea7a4ed788eb1fec1e7b9b10 |
| institution | Kabale University |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-e2fa1b54ea7a4ed788eb1fec1e7b9b102025-02-03T01:12:35ZengWileyGastroenterology Research and Practice1687-61211687-630X2018-01-01201810.1155/2018/83527568352756Long-Term Outcomes of Caustic Esophageal Stricture with Endoscopic Balloon Dilatation in Chinese ChildrenLan-Lan Geng0Cui-Ping Liang1Pei-Yu Chen2Qiang Wu3Min Yang4Hui-Wen Li5Zhao-Hui Xu6Lu Ren7Hong-Li Wang8Shunxian Cheng9Wan-Fu Xu10Yang Chen11Chao Zhang12Li-Ying Liu13Ding-You Li14Si-Tang Gong15Department of Gastroenterology, Guangzhou Women and Children’s Medical Center, 9 Jinsui Road, Guangzhou 510623, ChinaDepartment of Gastroenterology, Guangzhou Women and Children’s Medical Center, 9 Jinsui Road, Guangzhou 510623, ChinaDepartment of Gastroenterology, Guangzhou Women and Children’s Medical Center, 9 Jinsui Road, Guangzhou 510623, ChinaDepartment of Gastroenterology, Guangzhou Women and Children’s Medical Center, 9 Jinsui Road, Guangzhou 510623, ChinaDepartment of Gastroenterology, Guangzhou Women and Children’s Medical Center, 9 Jinsui Road, Guangzhou 510623, ChinaDepartment of Gastroenterology, Guangzhou Women and Children’s Medical Center, 9 Jinsui Road, Guangzhou 510623, ChinaDepartment of Gastroenterology, Guangzhou Women and Children’s Medical Center, 9 Jinsui Road, Guangzhou 510623, ChinaDepartment of Gastroenterology, Guangzhou Women and Children’s Medical Center, 9 Jinsui Road, Guangzhou 510623, ChinaDepartment of Gastroenterology, Guangzhou Women and Children’s Medical Center, 9 Jinsui Road, Guangzhou 510623, ChinaDepartment of Gastroenterology, Guangzhou Women and Children’s Medical Center, 9 Jinsui Road, Guangzhou 510623, ChinaDepartment of Gastroenterology, Guangzhou Women and Children’s Medical Center, 9 Jinsui Road, Guangzhou 510623, ChinaDepartment of Gastroenterology, Guangzhou Women and Children’s Medical Center, 9 Jinsui Road, Guangzhou 510623, ChinaDepartment of Gastroenterology, Guangzhou Women and Children’s Medical Center, 9 Jinsui Road, Guangzhou 510623, ChinaDepartment of Gastroenterology, Guangzhou Women and Children’s Medical Center, 9 Jinsui Road, Guangzhou 510623, ChinaDivision of Gastroenterology, Children’s Mercy Hospital, 2401 Gillham Road, Kansas City, MO 64108, USADepartment of Gastroenterology, Guangzhou Women and Children’s Medical Center, 9 Jinsui Road, Guangzhou 510623, ChinaCaustic esophageal stricture (CES) in children still occurs frequently in developing countries. We aimed to evaluate the long-term outcomes of endoscopic balloon dilatation (EBD) in treating CES in children and the influencing factors associated with outcome. We retrospectively reviewed the data of all patients who had a diagnosis of CES and underwent EBD from August 1, 2005, to December 31, 2014. The primary outcome was EBD success, which was defined as the maintenance of dysphagia-free status for at least 12 months after the last EBD. The secondary outcome was to analyze influencing factors associated with EBD success. Forty-three patients were included for analysis (29 males; mean age at first dilatation 44 months with range 121 months). 26 (60.5%) patients had long segment (>2 cm) stricture. A total of 168 EBD procedures were performed. Twenty-six (60.5%) patients were considered EBD success. Seventeen (39.5%) patients failed EBD and required stent placement and/or surgery. Patients in the EBD success group had significantly shorter stricture segments when compared to the EBD failure group (t=2.398, P=0.018, OR=3.206, 95% OR: 1.228–8.371). Seven (4.4%) esophageal perforations occurred in 6 patients after EBD. Stents were placed in 5 patients, and gastric tube esophagoplasty was performed in 14 patients. In conclusion, 26 (60.5%) of 43 children with CES had EBD success. Length of stricture was the main influencing factor associated with EBD treatment outcome.http://dx.doi.org/10.1155/2018/8352756 |
| spellingShingle | Lan-Lan Geng Cui-Ping Liang Pei-Yu Chen Qiang Wu Min Yang Hui-Wen Li Zhao-Hui Xu Lu Ren Hong-Li Wang Shunxian Cheng Wan-Fu Xu Yang Chen Chao Zhang Li-Ying Liu Ding-You Li Si-Tang Gong Long-Term Outcomes of Caustic Esophageal Stricture with Endoscopic Balloon Dilatation in Chinese Children Gastroenterology Research and Practice |
| title | Long-Term Outcomes of Caustic Esophageal Stricture with Endoscopic Balloon Dilatation in Chinese Children |
| title_full | Long-Term Outcomes of Caustic Esophageal Stricture with Endoscopic Balloon Dilatation in Chinese Children |
| title_fullStr | Long-Term Outcomes of Caustic Esophageal Stricture with Endoscopic Balloon Dilatation in Chinese Children |
| title_full_unstemmed | Long-Term Outcomes of Caustic Esophageal Stricture with Endoscopic Balloon Dilatation in Chinese Children |
| title_short | Long-Term Outcomes of Caustic Esophageal Stricture with Endoscopic Balloon Dilatation in Chinese Children |
| title_sort | long term outcomes of caustic esophageal stricture with endoscopic balloon dilatation in chinese children |
| url | http://dx.doi.org/10.1155/2018/8352756 |
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