Rodents and other small mammal reservoirs in plague foci in northeastern Brazil

Introduction: Plague is an acute, infectious zoonotic disease, primarily of wild rodents and their fleas, that affects humans and other mammals. In Brazil, several plague foci are located in the northeast region. Plague surveillance based on monitoring of rodents was discontinued in 2007, and the c...

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Main Authors: Erika de Cássia Vieira da Costa, Marise Sobreira, Nilma Cintra Leal, Alzira Maria Paiva de Almeida
Format: Article
Language:English
Published: The Journal of Infection in Developing Countries 2017-06-01
Series:Journal of Infection in Developing Countries
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Online Access:https://jidc.org/index.php/journal/article/view/8271
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author Erika de Cássia Vieira da Costa
Marise Sobreira
Nilma Cintra Leal
Alzira Maria Paiva de Almeida
author_facet Erika de Cássia Vieira da Costa
Marise Sobreira
Nilma Cintra Leal
Alzira Maria Paiva de Almeida
author_sort Erika de Cássia Vieira da Costa
collection DOAJ
description Introduction: Plague is an acute, infectious zoonotic disease, primarily of wild rodents and their fleas, that affects humans and other mammals. In Brazil, several plague foci are located in the northeast region. Plague surveillance based on monitoring of rodents was discontinued in 2007, and the current information on rodent populations is unsatisfactory. Our purpose was to update the information on rodents and other small mammals in plague foci in northeastern Brazil. Methodology: Nine surveys in the historically most important northeastern plague areas were conducted in 2013-2015. Results: In this study, 393 animals (13 rodent and four marsupial species) were entrapped. The plague bacterium Yersinia pestis was not detected in tissue sample cultures from the 225 animals that were analyzed. Eighty sera samples were analyzed for anti-F1 antibodies by hemagglutination (HA) and protein A ELISA tests, and all were negative, except for one marsupial, Monodelphis domestica, which was HA positive. Conclusions: Qualitative and quantitative differences in the animal populations were observed in the areas surveyed, and the antibody positive marsupial indicated that plague continues to circulate in the wild.
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institution Kabale University
issn 1972-2680
language English
publishDate 2017-06-01
publisher The Journal of Infection in Developing Countries
record_format Article
series Journal of Infection in Developing Countries
spelling doaj-art-e2f4b7c44659467e944687655095a80c2025-08-20T03:52:42ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802017-06-01110510.3855/jidc.8271Rodents and other small mammal reservoirs in plague foci in northeastern BrazilErika de Cássia Vieira da Costa0Marise Sobreira1Nilma Cintra Leal2Alzira Maria Paiva de Almeida3Center of Research Aggeu Magalhães, Recife, BrazilCenter of Research Aggeu Magalhães, Recife, BrazilCenter of Research Aggeu Magalhães, RecifeCenter of Research Aggeu Magalhães, Recife, Brazil Introduction: Plague is an acute, infectious zoonotic disease, primarily of wild rodents and their fleas, that affects humans and other mammals. In Brazil, several plague foci are located in the northeast region. Plague surveillance based on monitoring of rodents was discontinued in 2007, and the current information on rodent populations is unsatisfactory. Our purpose was to update the information on rodents and other small mammals in plague foci in northeastern Brazil. Methodology: Nine surveys in the historically most important northeastern plague areas were conducted in 2013-2015. Results: In this study, 393 animals (13 rodent and four marsupial species) were entrapped. The plague bacterium Yersinia pestis was not detected in tissue sample cultures from the 225 animals that were analyzed. Eighty sera samples were analyzed for anti-F1 antibodies by hemagglutination (HA) and protein A ELISA tests, and all were negative, except for one marsupial, Monodelphis domestica, which was HA positive. Conclusions: Qualitative and quantitative differences in the animal populations were observed in the areas surveyed, and the antibody positive marsupial indicated that plague continues to circulate in the wild. https://jidc.org/index.php/journal/article/view/8271PlagueAntibodiesYersinia pestisRodentsantibodiesMarsupials
spellingShingle Erika de Cássia Vieira da Costa
Marise Sobreira
Nilma Cintra Leal
Alzira Maria Paiva de Almeida
Rodents and other small mammal reservoirs in plague foci in northeastern Brazil
Journal of Infection in Developing Countries
Plague
Antibodies
Yersinia pestis
Rodents
antibodies
Marsupials
title Rodents and other small mammal reservoirs in plague foci in northeastern Brazil
title_full Rodents and other small mammal reservoirs in plague foci in northeastern Brazil
title_fullStr Rodents and other small mammal reservoirs in plague foci in northeastern Brazil
title_full_unstemmed Rodents and other small mammal reservoirs in plague foci in northeastern Brazil
title_short Rodents and other small mammal reservoirs in plague foci in northeastern Brazil
title_sort rodents and other small mammal reservoirs in plague foci in northeastern brazil
topic Plague
Antibodies
Yersinia pestis
Rodents
antibodies
Marsupials
url https://jidc.org/index.php/journal/article/view/8271
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AT marisesobreira rodentsandothersmallmammalreservoirsinplaguefociinnortheasternbrazil
AT nilmacintraleal rodentsandothersmallmammalreservoirsinplaguefociinnortheasternbrazil
AT alziramariapaivadealmeida rodentsandothersmallmammalreservoirsinplaguefociinnortheasternbrazil