Posterior Reversible Encephalopathy Syndrome Secondary to Hypercalcemia in a Teenager: A Case Report

This case details an atypical presentation of a common clinical condition, primary hyperparathyroidism. A 16-year-old girl with no medical history presented with status epilepticus and hypertension. She reported a 3-month history of asthenia, nausea, vomiting, polyuria, and weight loss, as well as a...

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Bibliographic Details
Main Authors: Valeria Roldan, Catalina Aron-Said, Patricia Bejar, Jose Cotrina, Giancarlo Sante, Hector Sosa, Arturo E. Villena
Format: Article
Language:English
Published: American College of Physicians 2024-11-01
Series:Annals of Internal Medicine: Clinical Cases
Online Access:https://www.acpjournals.org/doi/10.7326/aimcc.2024.0426
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Summary:This case details an atypical presentation of a common clinical condition, primary hyperparathyroidism. A 16-year-old girl with no medical history presented with status epilepticus and hypertension. She reported a 3-month history of asthenia, nausea, vomiting, polyuria, and weight loss, as well as an episode of sudden vision loss with persistent blurriness. Her serum calcium was 3.94 mmol/L and her level of parathyroid hormone was 28.16 pmol/L. T2-weighted magnetic resonance imaging of the brain revealed symmetrical bilateral occipito-parietal hyperintensities. Taken together, the clinical context and radiologic findings in this case suggested a diagnosis of posterior reversible encephalopathy syndrome. Hypercalcemia is a rare cause of posterior reversible encephalopathy syndrome.
ISSN:2767-7664