Expanding our Understanding of Atypical Antipsychotics: Acute Urinary Retention Secondary to Olanzapine

Antipsychotics are considered the most efficacious drugs in the treatment of schizophrenia and other psychotic disorders. While clinicians monitor for the onset of extrapyramidal symptoms (EPSs), many do not consider the antimuscarinic and histaminergic side effects that can occur with second genera...

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Main Authors: Hannah Mirzakhani, Mariam Rahim, Jacob Mathew
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Psychiatry
Online Access:http://dx.doi.org/10.1155/2020/6157548
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author Hannah Mirzakhani
Mariam Rahim
Jacob Mathew
author_facet Hannah Mirzakhani
Mariam Rahim
Jacob Mathew
author_sort Hannah Mirzakhani
collection DOAJ
description Antipsychotics are considered the most efficacious drugs in the treatment of schizophrenia and other psychotic disorders. While clinicians monitor for the onset of extrapyramidal symptoms (EPSs), many do not consider the antimuscarinic and histaminergic side effects that can occur with second generation antipsychotics. We present the case of a 62-year-old male who presented with acute urinary retention that was found to be due to the recent initiation of olanzapine. Gradual cessation of the medication and follow-up with urology revealed resolution of his symptoms. With the increasing demand for psychiatric care but limited psychiatric resources, more and more primary care physicians find themselves dealing with the complex challenges of mental illness and managing antipsychotic medications. As a result, coordinating care among multiple specialties and understanding the full profile of side effects that are associated with psychiatric medications can yield quicker diagnoses and improve patient care.
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spelling doaj-art-e2e1f18e46be41e596dc510da259d2a32025-08-20T03:21:07ZengWileyCase Reports in Psychiatry2090-682X2090-68382020-01-01202010.1155/2020/61575486157548Expanding our Understanding of Atypical Antipsychotics: Acute Urinary Retention Secondary to OlanzapineHannah Mirzakhani0Mariam Rahim1Jacob Mathew2Department of Medicine, Parkview Medical Center, Pueblo, CO 81003, USADepartment of Medicine, Parkview Medical Center, Pueblo, CO 81003, USADepartment of Medicine, Parkview Medical Center, Pueblo, CO 81003, USAAntipsychotics are considered the most efficacious drugs in the treatment of schizophrenia and other psychotic disorders. While clinicians monitor for the onset of extrapyramidal symptoms (EPSs), many do not consider the antimuscarinic and histaminergic side effects that can occur with second generation antipsychotics. We present the case of a 62-year-old male who presented with acute urinary retention that was found to be due to the recent initiation of olanzapine. Gradual cessation of the medication and follow-up with urology revealed resolution of his symptoms. With the increasing demand for psychiatric care but limited psychiatric resources, more and more primary care physicians find themselves dealing with the complex challenges of mental illness and managing antipsychotic medications. As a result, coordinating care among multiple specialties and understanding the full profile of side effects that are associated with psychiatric medications can yield quicker diagnoses and improve patient care.http://dx.doi.org/10.1155/2020/6157548
spellingShingle Hannah Mirzakhani
Mariam Rahim
Jacob Mathew
Expanding our Understanding of Atypical Antipsychotics: Acute Urinary Retention Secondary to Olanzapine
Case Reports in Psychiatry
title Expanding our Understanding of Atypical Antipsychotics: Acute Urinary Retention Secondary to Olanzapine
title_full Expanding our Understanding of Atypical Antipsychotics: Acute Urinary Retention Secondary to Olanzapine
title_fullStr Expanding our Understanding of Atypical Antipsychotics: Acute Urinary Retention Secondary to Olanzapine
title_full_unstemmed Expanding our Understanding of Atypical Antipsychotics: Acute Urinary Retention Secondary to Olanzapine
title_short Expanding our Understanding of Atypical Antipsychotics: Acute Urinary Retention Secondary to Olanzapine
title_sort expanding our understanding of atypical antipsychotics acute urinary retention secondary to olanzapine
url http://dx.doi.org/10.1155/2020/6157548
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AT mariamrahim expandingourunderstandingofatypicalantipsychoticsacuteurinaryretentionsecondarytoolanzapine
AT jacobmathew expandingourunderstandingofatypicalantipsychoticsacuteurinaryretentionsecondarytoolanzapine