Assessing short-term weather-induced immune response in Russian Far East residents with respiratory diseases
Objective — To identify criteria for contrasting meteorological changes affecting the temporal dynamics of the immune response in individuals with bronchopulmonary pathology in the maritime monsoon climate of Vladivostok. Methods — We examined 178 patients with stable chronic obstructive pulmonary...
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| Format: | Article |
| Language: | English |
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Limited liability company «Science and Innovations» (Saratov)
2023-06-01
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| Series: | Russian Open Medical Journal |
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| Online Access: | https://romj.org/node/528 |
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| author | Lyudmila V. Veremchuk Tatyana I. Vitkina Elena E. Mineeva Elena V. Kondratyeva |
| author_facet | Lyudmila V. Veremchuk Tatyana I. Vitkina Elena E. Mineeva Elena V. Kondratyeva |
| author_sort | Lyudmila V. Veremchuk |
| collection | DOAJ |
| description | Objective — To identify criteria for contrasting meteorological changes affecting the temporal dynamics of the immune response in individuals with bronchopulmonary pathology in the maritime monsoon climate of Vladivostok.
Methods — We examined 178 patients with stable chronic obstructive pulmonary disease (COPD) of mild and moderate severity, 212 patients with controlled bronchial asthma (BA) and 60 apparently healthy volunteers. We assessed the cumulative response of the components of adaptive and innate immune systems to the effects of day-to-day variability in temperature, air pressure and humidity, wind speed and direction, and precipitation relative to the day of the patient’s medical examination ± 2 days. The response of the immune system was measured by an integral indicator calculated as the ratio of the sum of statistically significant correlations (p<0.05) to the total sum of correlation matrix elements.
Results — The short-term compensatory severity and activity of the immune response to the weather in healthy people (∑D%=2.56; ∑r=117) was almost twice as high as the similar response in patients with COPD (∑D%=1.28; ∑r=72) or BA (∑D%=1.35; ∑r=69). The immune response of apparently healthy subjects to the action of specific meteorological factors on the day of medical examination was reduced by 40%, compared with the short-term response (±2 days) in patients with COPD, but the difference was not significant. The values of the criteria for the day-to-day contrast of influencing meteorological factors in apparently healthy patients were reduced.
Conclusion — The urban population in maritime monsoon climate exhibited weak and moderate weather-induced immune system responses. Wind regime, humidity and precipitation had a pronounced effect on the immune system. In patients with COPD and BA, the maximum pathogenic response of the immune system to the impact of climatic factors was observed within ±1 day. |
| format | Article |
| id | doaj-art-e2de587e55ef4da2bb6e892c791b7d71 |
| institution | DOAJ |
| issn | 2304-3415 |
| language | English |
| publishDate | 2023-06-01 |
| publisher | Limited liability company «Science and Innovations» (Saratov) |
| record_format | Article |
| series | Russian Open Medical Journal |
| spelling | doaj-art-e2de587e55ef4da2bb6e892c791b7d712025-08-20T03:19:17ZengLimited liability company «Science and Innovations» (Saratov)Russian Open Medical Journal2304-34152023-06-01122e020310.15275/rusomj.2023.0203Assessing short-term weather-induced immune response in Russian Far East residents with respiratory diseasesLyudmila V. VeremchukTatyana I. VitkinaElena E. MineevaElena V. KondratyevaObjective — To identify criteria for contrasting meteorological changes affecting the temporal dynamics of the immune response in individuals with bronchopulmonary pathology in the maritime monsoon climate of Vladivostok. Methods — We examined 178 patients with stable chronic obstructive pulmonary disease (COPD) of mild and moderate severity, 212 patients with controlled bronchial asthma (BA) and 60 apparently healthy volunteers. We assessed the cumulative response of the components of adaptive and innate immune systems to the effects of day-to-day variability in temperature, air pressure and humidity, wind speed and direction, and precipitation relative to the day of the patient’s medical examination ± 2 days. The response of the immune system was measured by an integral indicator calculated as the ratio of the sum of statistically significant correlations (p<0.05) to the total sum of correlation matrix elements. Results — The short-term compensatory severity and activity of the immune response to the weather in healthy people (∑D%=2.56; ∑r=117) was almost twice as high as the similar response in patients with COPD (∑D%=1.28; ∑r=72) or BA (∑D%=1.35; ∑r=69). The immune response of apparently healthy subjects to the action of specific meteorological factors on the day of medical examination was reduced by 40%, compared with the short-term response (±2 days) in patients with COPD, but the difference was not significant. The values of the criteria for the day-to-day contrast of influencing meteorological factors in apparently healthy patients were reduced. Conclusion — The urban population in maritime monsoon climate exhibited weak and moderate weather-induced immune system responses. Wind regime, humidity and precipitation had a pronounced effect on the immune system. In patients with COPD and BA, the maximum pathogenic response of the immune system to the impact of climatic factors was observed within ±1 day.https://romj.org/node/528immune systemshort-term meteoropathybronchopulmonary diseases |
| spellingShingle | Lyudmila V. Veremchuk Tatyana I. Vitkina Elena E. Mineeva Elena V. Kondratyeva Assessing short-term weather-induced immune response in Russian Far East residents with respiratory diseases Russian Open Medical Journal immune system short-term meteoropathy bronchopulmonary diseases |
| title | Assessing short-term weather-induced immune response in Russian Far East residents with respiratory diseases |
| title_full | Assessing short-term weather-induced immune response in Russian Far East residents with respiratory diseases |
| title_fullStr | Assessing short-term weather-induced immune response in Russian Far East residents with respiratory diseases |
| title_full_unstemmed | Assessing short-term weather-induced immune response in Russian Far East residents with respiratory diseases |
| title_short | Assessing short-term weather-induced immune response in Russian Far East residents with respiratory diseases |
| title_sort | assessing short term weather induced immune response in russian far east residents with respiratory diseases |
| topic | immune system short-term meteoropathy bronchopulmonary diseases |
| url | https://romj.org/node/528 |
| work_keys_str_mv | AT lyudmilavveremchuk assessingshorttermweatherinducedimmuneresponseinrussianfareastresidentswithrespiratorydiseases AT tatyanaivitkina assessingshorttermweatherinducedimmuneresponseinrussianfareastresidentswithrespiratorydiseases AT elenaemineeva assessingshorttermweatherinducedimmuneresponseinrussianfareastresidentswithrespiratorydiseases AT elenavkondratyeva assessingshorttermweatherinducedimmuneresponseinrussianfareastresidentswithrespiratorydiseases |