Acute Primary Adrenal Insufficiency after Hip Replacement in a Patient with Acute Intermittent Porphyria
Adrenal insufficiency is a potentially life-threatening condition when it occurs acutely, as in adrenal hemorrhage. Generally it is not reversible and requires chronic replacement therapy. Acute intermittent porphyria (AIP) is a rare genetic disease characterized by alterations in heme biosynthesis...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Case Reports in Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2018/2353172 |
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| author | Adele Latina Massimo Terzolo Anna Pia Giuseppe Reimondo Elena Castellano Micaela Pellegrino Giorgio Borretta |
| author_facet | Adele Latina Massimo Terzolo Anna Pia Giuseppe Reimondo Elena Castellano Micaela Pellegrino Giorgio Borretta |
| author_sort | Adele Latina |
| collection | DOAJ |
| description | Adrenal insufficiency is a potentially life-threatening condition when it occurs acutely, as in adrenal hemorrhage. Generally it is not reversible and requires chronic replacement therapy. Acute intermittent porphyria (AIP) is a rare genetic disease characterized by alterations in heme biosynthesis that result in accumulation of precursors in tissues. A crisis can be triggered by many conditions such as surgery and infections. Symptoms are similar to those of acute hypoadrenalism. Moreover, both conditions are characterized by hyponatremia. We describe the case of a postmenopausal woman known to be affected by AIP who developed after surgery a primary adrenal insufficiency associated with adrenal enlargement; the latter completely reverted in six months. |
| format | Article |
| id | doaj-art-e2de3408e380400cbeca349817b22e11 |
| institution | Kabale University |
| issn | 2090-6501 2090-651X |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Endocrinology |
| spelling | doaj-art-e2de3408e380400cbeca349817b22e112025-02-03T06:07:05ZengWileyCase Reports in Endocrinology2090-65012090-651X2018-01-01201810.1155/2018/23531722353172Acute Primary Adrenal Insufficiency after Hip Replacement in a Patient with Acute Intermittent PorphyriaAdele Latina0Massimo Terzolo1Anna Pia2Giuseppe Reimondo3Elena Castellano4Micaela Pellegrino5Giorgio Borretta6Division of Endocrinology, Diabetology and Metabolism, Santa Croce e Carle Hospital, Via M. Coppino 26, 12100 Cuneo, ItalyInternal Medicine 1, Department of Clinical and Biological Sciences, University of Turin, San Luigi Gonzaga Hospital, Regione Gonzole 10, Orbassano, 10043 Turin, ItalyInternal Medicine 1, Department of Clinical and Biological Sciences, University of Turin, San Luigi Gonzaga Hospital, Regione Gonzole 10, Orbassano, 10043 Turin, ItalyInternal Medicine 1, Department of Clinical and Biological Sciences, University of Turin, San Luigi Gonzaga Hospital, Regione Gonzole 10, Orbassano, 10043 Turin, ItalyDivision of Endocrinology, Diabetology and Metabolism, Santa Croce e Carle Hospital, Via M. Coppino 26, 12100 Cuneo, ItalyDivision of Endocrinology, Diabetology and Metabolism, Santa Croce e Carle Hospital, Via M. Coppino 26, 12100 Cuneo, ItalyDivision of Endocrinology, Diabetology and Metabolism, Santa Croce e Carle Hospital, Via M. Coppino 26, 12100 Cuneo, ItalyAdrenal insufficiency is a potentially life-threatening condition when it occurs acutely, as in adrenal hemorrhage. Generally it is not reversible and requires chronic replacement therapy. Acute intermittent porphyria (AIP) is a rare genetic disease characterized by alterations in heme biosynthesis that result in accumulation of precursors in tissues. A crisis can be triggered by many conditions such as surgery and infections. Symptoms are similar to those of acute hypoadrenalism. Moreover, both conditions are characterized by hyponatremia. We describe the case of a postmenopausal woman known to be affected by AIP who developed after surgery a primary adrenal insufficiency associated with adrenal enlargement; the latter completely reverted in six months.http://dx.doi.org/10.1155/2018/2353172 |
| spellingShingle | Adele Latina Massimo Terzolo Anna Pia Giuseppe Reimondo Elena Castellano Micaela Pellegrino Giorgio Borretta Acute Primary Adrenal Insufficiency after Hip Replacement in a Patient with Acute Intermittent Porphyria Case Reports in Endocrinology |
| title | Acute Primary Adrenal Insufficiency after Hip Replacement in a Patient with Acute Intermittent Porphyria |
| title_full | Acute Primary Adrenal Insufficiency after Hip Replacement in a Patient with Acute Intermittent Porphyria |
| title_fullStr | Acute Primary Adrenal Insufficiency after Hip Replacement in a Patient with Acute Intermittent Porphyria |
| title_full_unstemmed | Acute Primary Adrenal Insufficiency after Hip Replacement in a Patient with Acute Intermittent Porphyria |
| title_short | Acute Primary Adrenal Insufficiency after Hip Replacement in a Patient with Acute Intermittent Porphyria |
| title_sort | acute primary adrenal insufficiency after hip replacement in a patient with acute intermittent porphyria |
| url | http://dx.doi.org/10.1155/2018/2353172 |
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