Effects of a Meal Replacement on Body Composition and Metabolic Parameters among Subjects with Overweight or Obesity
Meal replacement plans are effective tools for weight loss and improvement of various clinical characteristics but not sustainable due to the severe energy restriction. The aim of the study was to evaluate the impact of meal replacement, specifically 388 kcal in total energy, on body composition and...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Journal of Obesity |
| Online Access: | http://dx.doi.org/10.1155/2018/2837367 |
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| author | Xiaohui Guo Yifan Xu Hairong He Hao Cai Jianfen Zhang Yibin Li Xinyu Yan Man Zhang Na Zhang Rolando L. Maddela Jessie Nicodemus-Johnson Guansheng Ma |
| author_facet | Xiaohui Guo Yifan Xu Hairong He Hao Cai Jianfen Zhang Yibin Li Xinyu Yan Man Zhang Na Zhang Rolando L. Maddela Jessie Nicodemus-Johnson Guansheng Ma |
| author_sort | Xiaohui Guo |
| collection | DOAJ |
| description | Meal replacement plans are effective tools for weight loss and improvement of various clinical characteristics but not sustainable due to the severe energy restriction. The aim of the study was to evaluate the impact of meal replacement, specifically 388 kcal in total energy, on body composition and metabolic parameters in individuals with overweight and obesity from a Chinese population. A parallel, randomized controlled trial was performed with 174 participants (ChiCTR-OOC-17012000). The intervention group (N=86) was provided with a dinner meal replacement, and the control group (N=88) continued their routine diet as before. Body composition and blood parameters were assessed at 0, 4, 8, and 12 weeks. A post hoc analysis (least significant difference (LSD) test), repeated measurements, and paired T-test were used to compare each variable within and between groups. Significant (p<0.001) improvements in body composition components were observed among the intervention group, including body weight (−4.3 ± 3.3%), body mass index (−4.3 ± 3.3%), waist circumference (−4.3 ± 4.4%), fat-free mass (−1.8 ± 2.9%), and body fat mass (−5.3 ± 8.8%). Body composition improvements corresponded with significant metabolic improvements of blood glucose (−4.7 ± 9.8%). Further improvements in visceral fat area (−7.7 ± 10.1%), accompanying with improvements in systolic (−3.7 ± 6.9%) and diastolic (−5.3 ± 7.7%) blood pressure, were only found in male subjects. To conclude, meal replacement intake with 388 kcal in total energy at dinner time for 12 weeks contributed to improvement in body composition and clinically significant metabolic parameters in both male and female participants with overweight/obesity. Additionally, glucose and blood pressure reduction were gender-specific highlighting the importance of gender stratification for design of nutritional intervention studies for improvement of health. |
| format | Article |
| id | doaj-art-e2d1ad2b3d69433aac44058214ee5654 |
| institution | Kabale University |
| issn | 2090-0708 2090-0716 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Obesity |
| spelling | doaj-art-e2d1ad2b3d69433aac44058214ee56542025-02-03T05:54:05ZengWileyJournal of Obesity2090-07082090-07162018-01-01201810.1155/2018/28373672837367Effects of a Meal Replacement on Body Composition and Metabolic Parameters among Subjects with Overweight or ObesityXiaohui Guo0Yifan Xu1Hairong He2Hao Cai3Jianfen Zhang4Yibin Li5Xinyu Yan6Man Zhang7Na Zhang8Rolando L. Maddela9Jessie Nicodemus-Johnson10Guansheng Ma11Department of Nutrition and Food Hygiene, School of Public Health, Peking University, 38 Xue Yuan Road, Haidian District, Beijing 100191, ChinaDepartment of Nutrition and Food Hygiene, School of Public Health, Peking University, 38 Xue Yuan Road, Haidian District, Beijing 100191, ChinaDepartment of Nutrition and Food Hygiene, School of Public Health, Peking University, 38 Xue Yuan Road, Haidian District, Beijing 100191, ChinaDepartment of Nutrition and Food Hygiene, School of Public Health, Peking University, 38 Xue Yuan Road, Haidian District, Beijing 100191, ChinaDepartment of Nutrition and Food Hygiene, School of Public Health, Peking University, 38 Xue Yuan Road, Haidian District, Beijing 100191, ChinaDepartment of Nutrition and Food Hygiene, School of Public Health, Peking University, 38 Xue Yuan Road, Haidian District, Beijing 100191, ChinaDepartment of Nutrition and Food Hygiene, School of Public Health, Peking University, 38 Xue Yuan Road, Haidian District, Beijing 100191, ChinaDepartment of Nutrition and Food Hygiene, School of Public Health, Peking University, 38 Xue Yuan Road, Haidian District, Beijing 100191, ChinaDepartment of Nutrition and Food Hygiene, School of Public Health, Peking University, 38 Xue Yuan Road, Haidian District, Beijing 100191, ChinaUSANA Health Sciences Inc., 3838 W Parkway Boulevard, West Valley City, UT 84120, USAUSANA Health Sciences Inc., 3838 W Parkway Boulevard, West Valley City, UT 84120, USADepartment of Nutrition and Food Hygiene, School of Public Health, Peking University, 38 Xue Yuan Road, Haidian District, Beijing 100191, ChinaMeal replacement plans are effective tools for weight loss and improvement of various clinical characteristics but not sustainable due to the severe energy restriction. The aim of the study was to evaluate the impact of meal replacement, specifically 388 kcal in total energy, on body composition and metabolic parameters in individuals with overweight and obesity from a Chinese population. A parallel, randomized controlled trial was performed with 174 participants (ChiCTR-OOC-17012000). The intervention group (N=86) was provided with a dinner meal replacement, and the control group (N=88) continued their routine diet as before. Body composition and blood parameters were assessed at 0, 4, 8, and 12 weeks. A post hoc analysis (least significant difference (LSD) test), repeated measurements, and paired T-test were used to compare each variable within and between groups. Significant (p<0.001) improvements in body composition components were observed among the intervention group, including body weight (−4.3 ± 3.3%), body mass index (−4.3 ± 3.3%), waist circumference (−4.3 ± 4.4%), fat-free mass (−1.8 ± 2.9%), and body fat mass (−5.3 ± 8.8%). Body composition improvements corresponded with significant metabolic improvements of blood glucose (−4.7 ± 9.8%). Further improvements in visceral fat area (−7.7 ± 10.1%), accompanying with improvements in systolic (−3.7 ± 6.9%) and diastolic (−5.3 ± 7.7%) blood pressure, were only found in male subjects. To conclude, meal replacement intake with 388 kcal in total energy at dinner time for 12 weeks contributed to improvement in body composition and clinically significant metabolic parameters in both male and female participants with overweight/obesity. Additionally, glucose and blood pressure reduction were gender-specific highlighting the importance of gender stratification for design of nutritional intervention studies for improvement of health.http://dx.doi.org/10.1155/2018/2837367 |
| spellingShingle | Xiaohui Guo Yifan Xu Hairong He Hao Cai Jianfen Zhang Yibin Li Xinyu Yan Man Zhang Na Zhang Rolando L. Maddela Jessie Nicodemus-Johnson Guansheng Ma Effects of a Meal Replacement on Body Composition and Metabolic Parameters among Subjects with Overweight or Obesity Journal of Obesity |
| title | Effects of a Meal Replacement on Body Composition and Metabolic Parameters among Subjects with Overweight or Obesity |
| title_full | Effects of a Meal Replacement on Body Composition and Metabolic Parameters among Subjects with Overweight or Obesity |
| title_fullStr | Effects of a Meal Replacement on Body Composition and Metabolic Parameters among Subjects with Overweight or Obesity |
| title_full_unstemmed | Effects of a Meal Replacement on Body Composition and Metabolic Parameters among Subjects with Overweight or Obesity |
| title_short | Effects of a Meal Replacement on Body Composition and Metabolic Parameters among Subjects with Overweight or Obesity |
| title_sort | effects of a meal replacement on body composition and metabolic parameters among subjects with overweight or obesity |
| url | http://dx.doi.org/10.1155/2018/2837367 |
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