Syringohydromyelia, syringobulbia and syringocephaly associated with Chiari – I malformation: A case report

Syringohydromyelia, syringobulbia, and syringocephaly are rare manifestations of Chiari-I malformation (CM-I), each resulting from disrupted cerebrospinal fluid dynamics. While syringomyelia is commonly associated with CM-I, the rostral extension of syrinx cavities into the brainstem (syringobulbia)...

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Main Authors: Nebil A. Shukralla, Etsehiwot Demeke, Fitsum A. Gemechu, Michael A. Negussie, Abebe Mekonnen, Mersha A. Woldemariam, Kibruyisfaw Z. Shumbash
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Radiology Case Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S193004332500367X
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author Nebil A. Shukralla
Etsehiwot Demeke
Fitsum A. Gemechu
Michael A. Negussie
Abebe Mekonnen
Mersha A. Woldemariam
Kibruyisfaw Z. Shumbash
author_facet Nebil A. Shukralla
Etsehiwot Demeke
Fitsum A. Gemechu
Michael A. Negussie
Abebe Mekonnen
Mersha A. Woldemariam
Kibruyisfaw Z. Shumbash
author_sort Nebil A. Shukralla
collection DOAJ
description Syringohydromyelia, syringobulbia, and syringocephaly are rare manifestations of Chiari-I malformation (CM-I), each resulting from disrupted cerebrospinal fluid dynamics. While syringomyelia is commonly associated with CM-I, the rostral extension of syrinx cavities into the brainstem (syringobulbia) and cerebral parenchyma (syringocephaly) is very rare, with limited cases reported globally. This case report describes a 40-year-old woman presenting with progressive neurological deficits, including hemiparesis, sensory disturbances, and bulbar symptoms. Magnetic resonance imaging revealed CM-I with a syringohydromyelic cavity extending from the cervicomedullary junction to the thoracic spinal cord, syringobulbia involving the brainstem, and syringocephaly affecting the left cerebral hemisphere, internal capsule, and basal ganglia. Following posterior fossa decompression, the patient experienced significant neurological improvement, including restored motor function and resolution of intracranial edema, although the cervical syrinx cavity remained stable. This case demonstrates the importance of early diagnosis and surgical intervention in managing these rare yet debilitating complications of CM-I, highlighting the potential for improved outcomes despite the complex and extensive nature of these lesions.
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spelling doaj-art-e2cca6e2d3f64e97ab2aa85f738b328e2025-08-20T02:30:55ZengElsevierRadiology Case Reports1930-04332025-08-012083793379710.1016/j.radcr.2025.04.068Syringohydromyelia, syringobulbia and syringocephaly associated with Chiari – I malformation: A case reportNebil A. Shukralla0Etsehiwot Demeke1Fitsum A. Gemechu2Michael A. Negussie3Abebe Mekonnen4Mersha A. Woldemariam5Kibruyisfaw Z. Shumbash6School of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia; Corresponding author.Department of Radiology, College of Health Sciences, Addis Ababa University, Addis Ababa, EthiopiaSchool of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, EthiopiaSchool of Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, EthiopiaDepartment of Radiology, College of Health Sciences, Addis Ababa University, Addis Ababa, EthiopiaDepartment of Surgery, College of Health Sciences, Addis Ababa University, EthiopiaDepartment of Surgery, College of Health Sciences, Addis Ababa University, EthiopiaSyringohydromyelia, syringobulbia, and syringocephaly are rare manifestations of Chiari-I malformation (CM-I), each resulting from disrupted cerebrospinal fluid dynamics. While syringomyelia is commonly associated with CM-I, the rostral extension of syrinx cavities into the brainstem (syringobulbia) and cerebral parenchyma (syringocephaly) is very rare, with limited cases reported globally. This case report describes a 40-year-old woman presenting with progressive neurological deficits, including hemiparesis, sensory disturbances, and bulbar symptoms. Magnetic resonance imaging revealed CM-I with a syringohydromyelic cavity extending from the cervicomedullary junction to the thoracic spinal cord, syringobulbia involving the brainstem, and syringocephaly affecting the left cerebral hemisphere, internal capsule, and basal ganglia. Following posterior fossa decompression, the patient experienced significant neurological improvement, including restored motor function and resolution of intracranial edema, although the cervical syrinx cavity remained stable. This case demonstrates the importance of early diagnosis and surgical intervention in managing these rare yet debilitating complications of CM-I, highlighting the potential for improved outcomes despite the complex and extensive nature of these lesions.http://www.sciencedirect.com/science/article/pii/S193004332500367XChiari-I malformationMagnetic resonance imagingSyringobulbiaSyringocephalySyringohydromyelia
spellingShingle Nebil A. Shukralla
Etsehiwot Demeke
Fitsum A. Gemechu
Michael A. Negussie
Abebe Mekonnen
Mersha A. Woldemariam
Kibruyisfaw Z. Shumbash
Syringohydromyelia, syringobulbia and syringocephaly associated with Chiari – I malformation: A case report
Radiology Case Reports
Chiari-I malformation
Magnetic resonance imaging
Syringobulbia
Syringocephaly
Syringohydromyelia
title Syringohydromyelia, syringobulbia and syringocephaly associated with Chiari – I malformation: A case report
title_full Syringohydromyelia, syringobulbia and syringocephaly associated with Chiari – I malformation: A case report
title_fullStr Syringohydromyelia, syringobulbia and syringocephaly associated with Chiari – I malformation: A case report
title_full_unstemmed Syringohydromyelia, syringobulbia and syringocephaly associated with Chiari – I malformation: A case report
title_short Syringohydromyelia, syringobulbia and syringocephaly associated with Chiari – I malformation: A case report
title_sort syringohydromyelia syringobulbia and syringocephaly associated with chiari i malformation a case report
topic Chiari-I malformation
Magnetic resonance imaging
Syringobulbia
Syringocephaly
Syringohydromyelia
url http://www.sciencedirect.com/science/article/pii/S193004332500367X
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