Value of the Ratio of Monocytes to Lymphocytes for Monitoring Tuberculosis Therapy

Objective. The objective of this study was to evaluate the change of the ratio of monocytes to lymphocytes in patients with active tuberculosis, such as to provide reference for clinical diagnosis and treatment. Methods. All data were collected from the clinical database of The Fifth People’s Hospit...

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Bibliographic Details
Main Authors: Wei Wang, Li-fei Wang, Yan-yan Liu, Fang Yang, Lei Zhu, Xian-hui Zhang
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Canadian Journal of Infectious Diseases and Medical Microbiology
Online Access:http://dx.doi.org/10.1155/2019/3270393
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Summary:Objective. The objective of this study was to evaluate the change of the ratio of monocytes to lymphocytes in patients with active tuberculosis, such as to provide reference for clinical diagnosis and treatment. Methods. All data were collected from the clinical database of The Fifth People’s Hospital of Taiyuan, China. A total of 151 patients who had newly diagnosed active tuberculosis with tuberculosis therapy in hospital and 129 healthy controls were selected. Results. Median ratio of monocytes to lymphocytes was 0.45 (IQR: 0.28–0.67) in patients before treatment and 0.32 (IQR: 0.25–0.46) on discharge (P<0.001). Conclusions. Ratio of monocytes to lymphocytes may be applied in diagnosis and the chemotherapeutic efficacy of active tuberculosis.
ISSN:1712-9532
1918-1493