A Case of Early-Stage Ovarian Carcinoid Tumor Metastasized to the Liver
We report a case of ovarian carcinoid tumor that recurred with multiple liver metastases and was successfully treated with chemoembolization. A 76-year-old woman was admitted to our hospital presented with abdominal distension and abnormal uterine bleeding for about 6 months. She presented with hype...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Case Reports in Obstetrics and Gynecology |
| Online Access: | http://dx.doi.org/10.1155/2012/961087 |
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| author | Seiji Kanayama Yoshihiko Yamada Yasuhito Tanase Shoji Haruta Akira Nagai Ryuji Kawaguchi Shozo Yoshida Naoto Furukawa Hidekazu Oi Hiroshi Kobayashi |
| author_facet | Seiji Kanayama Yoshihiko Yamada Yasuhito Tanase Shoji Haruta Akira Nagai Ryuji Kawaguchi Shozo Yoshida Naoto Furukawa Hidekazu Oi Hiroshi Kobayashi |
| author_sort | Seiji Kanayama |
| collection | DOAJ |
| description | We report a case of ovarian carcinoid tumor that recurred with multiple liver metastases and was successfully treated with chemoembolization. A 76-year-old woman was admitted to our hospital presented with abdominal distension and abnormal uterine bleeding for about 6 months. She presented with hyperestrogenic and androgenic manifestations such as vaginal bleeding with endometrial hyperplasia and hirsutism. Magnetic resonance (MR) imaging revealed a large solid and cystic ovarian tumor of 17 cm at maximum diameter. On the basis of the clinical diagnosis of sex cord stromal tumor containing a mature cystic teratoma, she underwent total abdominal hysterectomy and bilateral salpingo-oophorectomy. The pathology report revealed that the mass in the left ovary was a carcinoid tumor, insular type, with mature cystic teratoma. Two years after surgical treatment, multiple liver metastases were revealed by abdominal CT. Hepatic arterial infusion of cisplatin was performed for 2 courses, and multiple metastatic nodules have remarkably reduced. No established chemotherapy or radiation therapy treatments are currently available for recurrent or advanced carcinoid tumors. Our paper suggests that chemoembolization with cisplatin may be effective in treatment of patients with multiple liver metastases of ovarian carcinoid tumor. |
| format | Article |
| id | doaj-art-e2c7b69f1c55472e95a1982cadd4e59d |
| institution | DOAJ |
| issn | 2090-6684 2090-6692 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Obstetrics and Gynecology |
| spelling | doaj-art-e2c7b69f1c55472e95a1982cadd4e59d2025-08-20T03:21:06ZengWileyCase Reports in Obstetrics and Gynecology2090-66842090-66922012-01-01201210.1155/2012/961087961087A Case of Early-Stage Ovarian Carcinoid Tumor Metastasized to the LiverSeiji Kanayama0Yoshihiko Yamada1Yasuhito Tanase2Shoji Haruta3Akira Nagai4Ryuji Kawaguchi5Shozo Yoshida6Naoto Furukawa7Hidekazu Oi8Hiroshi Kobayashi9Department of Obstetrics and Gynecology, Nara Medical University, 840 Shijo-cho, Nara, Kashihara 634-8522, JapanDepartment of Obstetrics and Gynecology, Nara Medical University, 840 Shijo-cho, Nara, Kashihara 634-8522, JapanDepartment of Obstetrics and Gynecology, Nara Medical University, 840 Shijo-cho, Nara, Kashihara 634-8522, JapanDepartment of Obstetrics and Gynecology, Nara Medical University, 840 Shijo-cho, Nara, Kashihara 634-8522, JapanDepartment of Obstetrics and Gynecology, Nara Medical University, 840 Shijo-cho, Nara, Kashihara 634-8522, JapanDepartment of Obstetrics and Gynecology, Nara Medical University, 840 Shijo-cho, Nara, Kashihara 634-8522, JapanDepartment of Obstetrics and Gynecology, Nara Medical University, 840 Shijo-cho, Nara, Kashihara 634-8522, JapanDepartment of Obstetrics and Gynecology, Nara Medical University, 840 Shijo-cho, Nara, Kashihara 634-8522, JapanDepartment of Obstetrics and Gynecology, Nara Medical University, 840 Shijo-cho, Nara, Kashihara 634-8522, JapanDepartment of Obstetrics and Gynecology, Nara Medical University, 840 Shijo-cho, Nara, Kashihara 634-8522, JapanWe report a case of ovarian carcinoid tumor that recurred with multiple liver metastases and was successfully treated with chemoembolization. A 76-year-old woman was admitted to our hospital presented with abdominal distension and abnormal uterine bleeding for about 6 months. She presented with hyperestrogenic and androgenic manifestations such as vaginal bleeding with endometrial hyperplasia and hirsutism. Magnetic resonance (MR) imaging revealed a large solid and cystic ovarian tumor of 17 cm at maximum diameter. On the basis of the clinical diagnosis of sex cord stromal tumor containing a mature cystic teratoma, she underwent total abdominal hysterectomy and bilateral salpingo-oophorectomy. The pathology report revealed that the mass in the left ovary was a carcinoid tumor, insular type, with mature cystic teratoma. Two years after surgical treatment, multiple liver metastases were revealed by abdominal CT. Hepatic arterial infusion of cisplatin was performed for 2 courses, and multiple metastatic nodules have remarkably reduced. No established chemotherapy or radiation therapy treatments are currently available for recurrent or advanced carcinoid tumors. Our paper suggests that chemoembolization with cisplatin may be effective in treatment of patients with multiple liver metastases of ovarian carcinoid tumor.http://dx.doi.org/10.1155/2012/961087 |
| spellingShingle | Seiji Kanayama Yoshihiko Yamada Yasuhito Tanase Shoji Haruta Akira Nagai Ryuji Kawaguchi Shozo Yoshida Naoto Furukawa Hidekazu Oi Hiroshi Kobayashi A Case of Early-Stage Ovarian Carcinoid Tumor Metastasized to the Liver Case Reports in Obstetrics and Gynecology |
| title | A Case of Early-Stage Ovarian Carcinoid Tumor Metastasized to the Liver |
| title_full | A Case of Early-Stage Ovarian Carcinoid Tumor Metastasized to the Liver |
| title_fullStr | A Case of Early-Stage Ovarian Carcinoid Tumor Metastasized to the Liver |
| title_full_unstemmed | A Case of Early-Stage Ovarian Carcinoid Tumor Metastasized to the Liver |
| title_short | A Case of Early-Stage Ovarian Carcinoid Tumor Metastasized to the Liver |
| title_sort | case of early stage ovarian carcinoid tumor metastasized to the liver |
| url | http://dx.doi.org/10.1155/2012/961087 |
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