Artificial removal of the zona pellucida at the pronuclear stage: an exploratory study to improve embryo fragmentation

Artificial removal of the zona pellucida at the pronuclear stage: an exploratory study to improve embryo fragmentation

Objective: To investigate whether artificial removal of zona pellucida (ZP) at the pronuclear stage improves good-quality embryos and blastocyst development in patients with difficulty conceiving because of severe fragmentation in early-cleavage stage. Design: Exploratory investigation. Setting: Rep...

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Bibliographic Details
Main Authors: Keitaro Yumoto, B.Sc., Toko Shimura, B.Sc., Minori Kawamoto, M.Sc., Minako Sugishima, B.Sc., Yasuyuki Mio, M.D., Ph.D.
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:F&S Reports
Subjects:
Zona pellucida
cytoplasmic fragmentation
blastocyst development
human embryo
ZP-free culture
Online Access:http://www.sciencedirect.com/science/article/pii/S2666334124000928
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