Effective strategies for isolating DNA from members of Asteraceae with high concentrations of secondary metabolites

The Asteraceae are the largest plant family but among the least studied at the genome level. Our work investigated practical methods to reduce the influence of secondary metabolites – specifically, phenolic compounds – on the extraction of DNA from Silphium spp. This genus is in the Heliantheae trib...

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Main Authors: Dustin W Bailey, Ziv Attia, Stephan Reinert, Brent S Hulke, Nolan C Kane
Format: Article
Language:English
Published: Taylor & Francis Group 2022-03-01
Series:BioTechniques
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Online Access:https://www.future-science.com/doi/10.2144/btn-2021-0050
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author Dustin W Bailey
Ziv Attia
Stephan Reinert
Brent S Hulke
Nolan C Kane
author_facet Dustin W Bailey
Ziv Attia
Stephan Reinert
Brent S Hulke
Nolan C Kane
author_sort Dustin W Bailey
collection DOAJ
description The Asteraceae are the largest plant family but among the least studied at the genome level. Our work investigated practical methods to reduce the influence of secondary metabolites – specifically, phenolic compounds – on the extraction of DNA from Silphium spp. This genus is in the Heliantheae tribe of Asteraceae that also includes sunflower (Helianthus annuus). Three methods were attempted in Silphium, with varying condition and age of the leaf sample. A modified cetyl trimethylammonium bromide (CTAB) method on young leaves resulted in the best DNA yield, with sufficient sample purity. No perceptible difference was observed between fresh and lyophilized samples for any extraction method or leaf age. These results provide an excellent basis for DNA extraction of difficult plant samples.
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1940-9818
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spelling doaj-art-e2bec8df3c534fd682d2ffacac19db312025-08-20T02:25:34ZengTaylor & Francis GroupBioTechniques0736-62051940-98182022-03-01723858910.2144/btn-2021-0050Effective strategies for isolating DNA from members of Asteraceae with high concentrations of secondary metabolitesDustin W Bailey0Ziv Attia1Stephan Reinert2Brent S Hulke3Nolan C Kane41Ecology & Evolutionary Biology Department, University of Colorado, Boulder, CO 80309, USA1Ecology & Evolutionary Biology Department, University of Colorado, Boulder, CO 80309, USA1Ecology & Evolutionary Biology Department, University of Colorado, Boulder, CO 80309, USA3Sunflower and Plant Biology Research Unit, USDA-ARS Edward T. Schafer Agricultural Research Center, Fargo, ND 58102, USA1Ecology & Evolutionary Biology Department, University of Colorado, Boulder, CO 80309, USAThe Asteraceae are the largest plant family but among the least studied at the genome level. Our work investigated practical methods to reduce the influence of secondary metabolites – specifically, phenolic compounds – on the extraction of DNA from Silphium spp. This genus is in the Heliantheae tribe of Asteraceae that also includes sunflower (Helianthus annuus). Three methods were attempted in Silphium, with varying condition and age of the leaf sample. A modified cetyl trimethylammonium bromide (CTAB) method on young leaves resulted in the best DNA yield, with sufficient sample purity. No perceptible difference was observed between fresh and lyophilized samples for any extraction method or leaf age. These results provide an excellent basis for DNA extraction of difficult plant samples.https://www.future-science.com/doi/10.2144/btn-2021-0050CTABDNA extractionsecondary metabolitesSilphiumsodium metabisulfite
spellingShingle Dustin W Bailey
Ziv Attia
Stephan Reinert
Brent S Hulke
Nolan C Kane
Effective strategies for isolating DNA from members of Asteraceae with high concentrations of secondary metabolites
BioTechniques
CTAB
DNA extraction
secondary metabolites
Silphium
sodium metabisulfite
title Effective strategies for isolating DNA from members of Asteraceae with high concentrations of secondary metabolites
title_full Effective strategies for isolating DNA from members of Asteraceae with high concentrations of secondary metabolites
title_fullStr Effective strategies for isolating DNA from members of Asteraceae with high concentrations of secondary metabolites
title_full_unstemmed Effective strategies for isolating DNA from members of Asteraceae with high concentrations of secondary metabolites
title_short Effective strategies for isolating DNA from members of Asteraceae with high concentrations of secondary metabolites
title_sort effective strategies for isolating dna from members of asteraceae with high concentrations of secondary metabolites
topic CTAB
DNA extraction
secondary metabolites
Silphium
sodium metabisulfite
url https://www.future-science.com/doi/10.2144/btn-2021-0050
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