Next generation sequencing reveals the mutation landscape of Chinese MDS patients and the association between mutations and AML transformations

Next generation sequencing reveals the mutation landscape of Chinese MDS patients and the association between mutations and AML transformations

Background/Objective Approximately 30% of patients with MDS eventually develop to acute myeloid leukemia (AML). Our study aimed to investigate the mutation landscape of Chinese MDS patients and identify the mutated genes which are closely implicated in the transformation of MDS to AML.Methods In tot...

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Bibliographic Details
Main Authors: Yu Liu, Huanchen Cheng, Mei Cheng, Meng Sun, Jun Ma, Tiejun Gong
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Hematology
Subjects:
Myelodysplastic syndromes
transformation
acute myeloid leukemia
mutation
predictive model
Online Access:https://www.tandfonline.com/doi/10.1080/16078454.2024.2392469
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