Disorders of the hemostasis system while doing coronary shunting on a working heart
Objective. To investigate the connection between application of solutions for infusion and parameters of the hemostasis system while the elective operations performance of coronary shunting on the working heart. Materials and methods. The results of examination and surgical treatment were analyze...
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Liga-Inform ltd.
2019-07-01
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| Series: | Клінічна хірургія |
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| Online Access: | https://hirurgiya.com.ua/index.php/journal/article/view/698 |
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| author | A. P. Mazur P. V. Gurin M. M. Babich |
| author_facet | A. P. Mazur P. V. Gurin M. M. Babich |
| author_sort | A. P. Mazur |
| collection | DOAJ |
| description | Objective. To investigate the connection between application of solutions for infusion and parameters of the hemostasis system while the elective operations performance of coronary shunting on the working heart.
Materials and methods. The results of examination and surgical treatment were analyzed in 80 patients, in whom coronary shunting on the working heart was conducted. The patients were divided into three groups: the Investigation Group I (IG I) – 20 patients, in whom colloidal solution of hydroxyethyl starch (HES) 130/0.4 was applied intraoperatively, the Investigation Group II (IG II) - 20 patients, in whom colloidal 4% solution of gelatin was used intraoperatively, and a Control Group, consisted of 40 patients, in whom only crystalloidal solutions were included in the infusion therapy program. The coagulation hemostasis indices, the blood loss volume and the need for hemotransfusion were compared.
Results. In the IG I patients the volume of perioperative blood loss was more than in the IG II patients – (615 ± 191) and (438 ± 62) ml, accordingly (p=0.0003), and the coagulation hemostasis indices were trustworthily lower at the operation ending, demanding the erythrocytic mass transfusion doing in 3 (15%) patients. The IG II patients, comparing with the Control Group, suffered more volume of the blood loss - (560 ± 164) and (438 ± 62) ml, accordingly (p=0,02), and the changes in the coagulation indices, similar to changes in patients of the IG I, comparing with the Control Group patients. Any patient from the IG II needed hemotransfusion perioperatively.
Conclusion. Application of colloidal solutions while doing elective operations of CSH on the working heart leads to disorder of coagulation hemostasis, the intraoperative blood loss and the need for hemotransfusion enhancement. |
| format | Article |
| id | doaj-art-e2a7cfb0a2194932b79d8d2520eaf54d |
| institution | DOAJ |
| issn | 0023-2130 2522-1396 |
| language | English |
| publishDate | 2019-07-01 |
| publisher | Liga-Inform ltd. |
| record_format | Article |
| series | Клінічна хірургія |
| spelling | doaj-art-e2a7cfb0a2194932b79d8d2520eaf54d2025-08-20T02:51:03ZengLiga-Inform ltd.Клінічна хірургія0023-21302522-13962019-07-01867232610.26779/2522-1396.2019.07.23698Disorders of the hemostasis system while doing coronary shunting on a working heartA. P. Mazur0P. V. Gurin1M. M. Babich2Shalimov National Institute of Surgery and Transplantology, KyivShalimov National Institute of Surgery and Transplantology, KyivShalimov National Institute of Surgery and Transplantology, KyivObjective. To investigate the connection between application of solutions for infusion and parameters of the hemostasis system while the elective operations performance of coronary shunting on the working heart. Materials and methods. The results of examination and surgical treatment were analyzed in 80 patients, in whom coronary shunting on the working heart was conducted. The patients were divided into three groups: the Investigation Group I (IG I) – 20 patients, in whom colloidal solution of hydroxyethyl starch (HES) 130/0.4 was applied intraoperatively, the Investigation Group II (IG II) - 20 patients, in whom colloidal 4% solution of gelatin was used intraoperatively, and a Control Group, consisted of 40 patients, in whom only crystalloidal solutions were included in the infusion therapy program. The coagulation hemostasis indices, the blood loss volume and the need for hemotransfusion were compared. Results. In the IG I patients the volume of perioperative blood loss was more than in the IG II patients – (615 ± 191) and (438 ± 62) ml, accordingly (p=0.0003), and the coagulation hemostasis indices were trustworthily lower at the operation ending, demanding the erythrocytic mass transfusion doing in 3 (15%) patients. The IG II patients, comparing with the Control Group, suffered more volume of the blood loss - (560 ± 164) and (438 ± 62) ml, accordingly (p=0,02), and the changes in the coagulation indices, similar to changes in patients of the IG I, comparing with the Control Group patients. Any patient from the IG II needed hemotransfusion perioperatively. Conclusion. Application of colloidal solutions while doing elective operations of CSH on the working heart leads to disorder of coagulation hemostasis, the intraoperative blood loss and the need for hemotransfusion enhancement.https://hirurgiya.com.ua/index.php/journal/article/view/698coagulation hemostasis; colloidal solutions; blood loss; hemotransfusion. |
| spellingShingle | A. P. Mazur P. V. Gurin M. M. Babich Disorders of the hemostasis system while doing coronary shunting on a working heart Клінічна хірургія coagulation hemostasis; colloidal solutions; blood loss; hemotransfusion. |
| title | Disorders of the hemostasis system while doing coronary shunting on a working heart |
| title_full | Disorders of the hemostasis system while doing coronary shunting on a working heart |
| title_fullStr | Disorders of the hemostasis system while doing coronary shunting on a working heart |
| title_full_unstemmed | Disorders of the hemostasis system while doing coronary shunting on a working heart |
| title_short | Disorders of the hemostasis system while doing coronary shunting on a working heart |
| title_sort | disorders of the hemostasis system while doing coronary shunting on a working heart |
| topic | coagulation hemostasis; colloidal solutions; blood loss; hemotransfusion. |
| url | https://hirurgiya.com.ua/index.php/journal/article/view/698 |
| work_keys_str_mv | AT apmazur disordersofthehemostasissystemwhiledoingcoronaryshuntingonaworkingheart AT pvgurin disordersofthehemostasissystemwhiledoingcoronaryshuntingonaworkingheart AT mmbabich disordersofthehemostasissystemwhiledoingcoronaryshuntingonaworkingheart |