Association of direct oral anticoagulant-proton pump inhibitor cotherapy with adverse outcomes: protocol for a population-based cohort study
Introduction Proton pump inhibitors (PPIs) are widely used for primary and secondary prevention of upper gastrointestinal bleeding. However, there remains controversy about the overall net clinical benefit of PPIs (omeprazole, rabeprazole, pantoprazole, lansoprazole) when coprescribed with direct or...
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Main Authors: | Lehana Thabane, Lawrence Mbuagbaw, Michael Paterson, Laura Targownik, Mei Wang, Anne Holbrook, Deborah Siegal |
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Format: | Article |
Language: | English |
Published: |
BMJ Publishing Group
2022-06-01
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Series: | BMJ Open |
Online Access: | https://bmjopen.bmj.com/content/12/6/e057991.full |
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