Strongyloides Hyperinfection in a Renal Transplant Patient: Always Be on the Lookout

We present a case of a 71-year-old Vietnamese man with chronic kidney disease secondary to adult polycystic kidney disease. He had been a prisoner of war before undergoing a successful cadaveric renal transplant in the United States. He presented to clinic one year after the transplant with gross he...

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Main Authors: Murtaza Mazhar, Ijlal Akbar Ali, Nelson Iván Agudelo Higuita
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Infectious Diseases
Online Access:http://dx.doi.org/10.1155/2017/2953805
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author Murtaza Mazhar
Ijlal Akbar Ali
Nelson Iván Agudelo Higuita
author_facet Murtaza Mazhar
Ijlal Akbar Ali
Nelson Iván Agudelo Higuita
author_sort Murtaza Mazhar
collection DOAJ
description We present a case of a 71-year-old Vietnamese man with chronic kidney disease secondary to adult polycystic kidney disease. He had been a prisoner of war before undergoing a successful cadaveric renal transplant in the United States. He presented to clinic one year after the transplant with gross hematuria, productive cough, intermittent chills, and weight loss. Long standing peripheral eosinophilia of 600–1200/μL triggered further evaluation. A wet mount of stool revealed Strongyloides stercoralis larvae. A computed tomography (CT) of chest showed findings suggestive of extension of the infection to the lungs. The patient was treated with a three-week course of ivermectin with complete resolution of signs, symptoms, peripheral eosinophilia, and the positive IgG serology. Strongyloides infection in renal transplant patient is very rare and often presents with hyperinfection, associated with high mortality rates. The American Transplant Society recommends pretransplant screening with stool examination and Strongyloides stercoralis antibody in recipients and donors from endemic areas or with eosinophilia. It is imperative that healthcare professionals involved in the care of these individuals be cognizant of these recommendations as it is a very preventable and treatable entity.
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spelling doaj-art-e2954de32f1e440393dbdbec3cf7c65e2025-02-03T06:07:30ZengWileyCase Reports in Infectious Diseases2090-66252090-66332017-01-01201710.1155/2017/29538052953805Strongyloides Hyperinfection in a Renal Transplant Patient: Always Be on the LookoutMurtaza Mazhar0Ijlal Akbar Ali1Nelson Iván Agudelo Higuita2Department of Internal Medicine, Suite 6300, 800 Stanton L Young Boulevard, Oklahoma University Health Sciences Center, Oklahoma City, OK 73104, USADepartment of Internal Medicine, Suite 6300, 800 Stanton L Young Boulevard, Oklahoma University Health Sciences Center, Oklahoma City, OK 73104, USADepartment of Infectious Diseases, Suite 7300, 800 Stanton L Young Boulevard, Oklahoma University Health Sciences Center, Oklahoma City, OK 73104, USAWe present a case of a 71-year-old Vietnamese man with chronic kidney disease secondary to adult polycystic kidney disease. He had been a prisoner of war before undergoing a successful cadaveric renal transplant in the United States. He presented to clinic one year after the transplant with gross hematuria, productive cough, intermittent chills, and weight loss. Long standing peripheral eosinophilia of 600–1200/μL triggered further evaluation. A wet mount of stool revealed Strongyloides stercoralis larvae. A computed tomography (CT) of chest showed findings suggestive of extension of the infection to the lungs. The patient was treated with a three-week course of ivermectin with complete resolution of signs, symptoms, peripheral eosinophilia, and the positive IgG serology. Strongyloides infection in renal transplant patient is very rare and often presents with hyperinfection, associated with high mortality rates. The American Transplant Society recommends pretransplant screening with stool examination and Strongyloides stercoralis antibody in recipients and donors from endemic areas or with eosinophilia. It is imperative that healthcare professionals involved in the care of these individuals be cognizant of these recommendations as it is a very preventable and treatable entity.http://dx.doi.org/10.1155/2017/2953805
spellingShingle Murtaza Mazhar
Ijlal Akbar Ali
Nelson Iván Agudelo Higuita
Strongyloides Hyperinfection in a Renal Transplant Patient: Always Be on the Lookout
Case Reports in Infectious Diseases
title Strongyloides Hyperinfection in a Renal Transplant Patient: Always Be on the Lookout
title_full Strongyloides Hyperinfection in a Renal Transplant Patient: Always Be on the Lookout
title_fullStr Strongyloides Hyperinfection in a Renal Transplant Patient: Always Be on the Lookout
title_full_unstemmed Strongyloides Hyperinfection in a Renal Transplant Patient: Always Be on the Lookout
title_short Strongyloides Hyperinfection in a Renal Transplant Patient: Always Be on the Lookout
title_sort strongyloides hyperinfection in a renal transplant patient always be on the lookout
url http://dx.doi.org/10.1155/2017/2953805
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