A case of primary peripheral T-cell type non-Hodgkin lymphoma originating in the iris: Clinico-pathological findings
Background. The ocular adnexal region is the primary localization of extranodal lymphoma in 5% to 15% of all Non-Hodgkin lymphoma. Intraocular lymphoma of T-cell origin is extremely rare and such sites of infiltration have been rarely observed in clinical examination. Case report. We presented a...
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Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade
2010-01-01
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| Series: | Vojnosanitetski Pregled |
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| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2010/0042-84501012025M.pdf |
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| author | Mihaljević Biljana Sretenović Aleksandra Jaković Ljubomir Peruničić-Jovanović Maja Kovačević Dragana Rašić Dejan Latković Zoran |
| author_facet | Mihaljević Biljana Sretenović Aleksandra Jaković Ljubomir Peruničić-Jovanović Maja Kovačević Dragana Rašić Dejan Latković Zoran |
| author_sort | Mihaljević Biljana |
| collection | DOAJ |
| description | Background. The ocular adnexal region is the primary localization of extranodal lymphoma in 5% to 15% of all Non-Hodgkin lymphoma. Intraocular lymphoma of T-cell origin is extremely rare and such sites of infiltration have been rarely observed in clinical examination. Case report. We presented a 56-year-old man with iris infiltration by primary intraocular peripheral T-cell lymphoma. The patient was in clinical stage I BE and the treatment was initiated according to cyclophosphamide, hydroxydaunorubicin, oncovin, prednisone (CHOP) regimen. When the second course of the therapy was scheduled, the patient developed central nervous system lymphoma infiltration. Although De Angelis regimen was used, 3 months after the diagnosis was established, lethal outcome ensued due to disease progression. Conclusion. According to our experience we can conclude that further therapeutical approach to patients with primary intraocular Tcell lymphoma requires modification of conventional treatment regimens. The lower median survival in these patients suggests that the disease may be of more aggressive course. |
| format | Article |
| id | doaj-art-e283e30ec08c4d6895fd1c19ccccaa3e |
| institution | OA Journals |
| issn | 0042-8450 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj-art-e283e30ec08c4d6895fd1c19ccccaa3e2025-08-20T02:04:18ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502010-01-0167121025102810.2298/VSP1012025MA case of primary peripheral T-cell type non-Hodgkin lymphoma originating in the iris: Clinico-pathological findingsMihaljević BiljanaSretenović AleksandraJaković LjubomirPeruničić-Jovanović MajaKovačević DraganaRašić DejanLatković ZoranBackground. The ocular adnexal region is the primary localization of extranodal lymphoma in 5% to 15% of all Non-Hodgkin lymphoma. Intraocular lymphoma of T-cell origin is extremely rare and such sites of infiltration have been rarely observed in clinical examination. Case report. We presented a 56-year-old man with iris infiltration by primary intraocular peripheral T-cell lymphoma. The patient was in clinical stage I BE and the treatment was initiated according to cyclophosphamide, hydroxydaunorubicin, oncovin, prednisone (CHOP) regimen. When the second course of the therapy was scheduled, the patient developed central nervous system lymphoma infiltration. Although De Angelis regimen was used, 3 months after the diagnosis was established, lethal outcome ensued due to disease progression. Conclusion. According to our experience we can conclude that further therapeutical approach to patients with primary intraocular Tcell lymphoma requires modification of conventional treatment regimens. The lower median survival in these patients suggests that the disease may be of more aggressive course.http://www.doiserbia.nb.rs/img/doi/0042-8450/2010/0042-84501012025M.pdflymphoma, non-Hodgkiniris diseasesdiagnosisneoplasm staginghistological techniquestherapeuticstreatment outcome. |
| spellingShingle | Mihaljević Biljana Sretenović Aleksandra Jaković Ljubomir Peruničić-Jovanović Maja Kovačević Dragana Rašić Dejan Latković Zoran A case of primary peripheral T-cell type non-Hodgkin lymphoma originating in the iris: Clinico-pathological findings Vojnosanitetski Pregled lymphoma, non-Hodgkin iris diseases diagnosis neoplasm staging histological techniques therapeutics treatment outcome. |
| title | A case of primary peripheral T-cell type non-Hodgkin lymphoma originating in the iris: Clinico-pathological findings |
| title_full | A case of primary peripheral T-cell type non-Hodgkin lymphoma originating in the iris: Clinico-pathological findings |
| title_fullStr | A case of primary peripheral T-cell type non-Hodgkin lymphoma originating in the iris: Clinico-pathological findings |
| title_full_unstemmed | A case of primary peripheral T-cell type non-Hodgkin lymphoma originating in the iris: Clinico-pathological findings |
| title_short | A case of primary peripheral T-cell type non-Hodgkin lymphoma originating in the iris: Clinico-pathological findings |
| title_sort | case of primary peripheral t cell type non hodgkin lymphoma originating in the iris clinico pathological findings |
| topic | lymphoma, non-Hodgkin iris diseases diagnosis neoplasm staging histological techniques therapeutics treatment outcome. |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2010/0042-84501012025M.pdf |
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