Threshold Dynamics and Competitive Exclusion in a Virus Infection Model with General Incidence Function and Density-Dependent Diffusion

In this paper, we investigate single-strain and multistrain viral infection models with general incidence function and density-dependent diffusion subject to the homogeneous Neumann boundary conditions. For the single-strain viral infection model, by using the linearization method and constructing a...

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Main Authors: Xiaosong Tang, Zhiwei Wang, Jianping Yang
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Complexity
Online Access:http://dx.doi.org/10.1155/2020/4923856
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author Xiaosong Tang
Zhiwei Wang
Jianping Yang
author_facet Xiaosong Tang
Zhiwei Wang
Jianping Yang
author_sort Xiaosong Tang
collection DOAJ
description In this paper, we investigate single-strain and multistrain viral infection models with general incidence function and density-dependent diffusion subject to the homogeneous Neumann boundary conditions. For the single-strain viral infection model, by using the linearization method and constructing appropriate Lyapunov functionals, we obtain that the global threshold dynamics of the model is determined by the reproductive numbers for viral infection ℛ0. For the multistrain viral infection model, we have discussed the competitive exclusion problem. If the reproduction number ℛi for strain i is maximal and larger than one, the steady state Ei corresponding to the strain i is globally stable. Thus, competitive exclusion happens and all other strains die out except strain i. Meanwhile, we can prove that the single-strain and multistrain viral infection models are well posed. Furthermore, numerical simulations are also carried out to illustrate the theoretical results, which is seldom seen in the relevant known literatures.
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spelling doaj-art-e26fac849d5e403b94121b73158f87eb2025-02-03T01:04:39ZengWileyComplexity1076-27871099-05262020-01-01202010.1155/2020/49238564923856Threshold Dynamics and Competitive Exclusion in a Virus Infection Model with General Incidence Function and Density-Dependent DiffusionXiaosong Tang0Zhiwei Wang1Jianping Yang2School of Mathematics and Physics, Jinggangshan University, Ji’an 343009, ChinaSchool of Mathematics and Physics, Jinggangshan University, Ji’an 343009, ChinaSchool of Electronics and Information Engineering, Jinggangshan University, Ji’an 343009, ChinaIn this paper, we investigate single-strain and multistrain viral infection models with general incidence function and density-dependent diffusion subject to the homogeneous Neumann boundary conditions. For the single-strain viral infection model, by using the linearization method and constructing appropriate Lyapunov functionals, we obtain that the global threshold dynamics of the model is determined by the reproductive numbers for viral infection ℛ0. For the multistrain viral infection model, we have discussed the competitive exclusion problem. If the reproduction number ℛi for strain i is maximal and larger than one, the steady state Ei corresponding to the strain i is globally stable. Thus, competitive exclusion happens and all other strains die out except strain i. Meanwhile, we can prove that the single-strain and multistrain viral infection models are well posed. Furthermore, numerical simulations are also carried out to illustrate the theoretical results, which is seldom seen in the relevant known literatures.http://dx.doi.org/10.1155/2020/4923856
spellingShingle Xiaosong Tang
Zhiwei Wang
Jianping Yang
Threshold Dynamics and Competitive Exclusion in a Virus Infection Model with General Incidence Function and Density-Dependent Diffusion
Complexity
title Threshold Dynamics and Competitive Exclusion in a Virus Infection Model with General Incidence Function and Density-Dependent Diffusion
title_full Threshold Dynamics and Competitive Exclusion in a Virus Infection Model with General Incidence Function and Density-Dependent Diffusion
title_fullStr Threshold Dynamics and Competitive Exclusion in a Virus Infection Model with General Incidence Function and Density-Dependent Diffusion
title_full_unstemmed Threshold Dynamics and Competitive Exclusion in a Virus Infection Model with General Incidence Function and Density-Dependent Diffusion
title_short Threshold Dynamics and Competitive Exclusion in a Virus Infection Model with General Incidence Function and Density-Dependent Diffusion
title_sort threshold dynamics and competitive exclusion in a virus infection model with general incidence function and density dependent diffusion
url http://dx.doi.org/10.1155/2020/4923856
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