Novel use of adjuvant proton beam therapy in patient with pelvic renal transplant diagnosed with stage IB3 cervical adenocarcinoma

Cervical adenocarcinoma is the second most common histology of cervical cancer and treatment can involve surgery, radiotherapy, systemic therapy, and any combination of the three. Photon external beam radiation therapy and brachytherapy have been the mainstay of radiation treatment options for cervi...

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Main Authors: Pedro Versuti Del Cioppo Vasques, Jamie N. Bakkum-Gamez, Patrick G. Dean, Jeremy F. Molligan, Allison E. Garda
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Gynecologic Oncology Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2352578924001991
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author Pedro Versuti Del Cioppo Vasques
Jamie N. Bakkum-Gamez
Patrick G. Dean
Jeremy F. Molligan
Allison E. Garda
author_facet Pedro Versuti Del Cioppo Vasques
Jamie N. Bakkum-Gamez
Patrick G. Dean
Jeremy F. Molligan
Allison E. Garda
author_sort Pedro Versuti Del Cioppo Vasques
collection DOAJ
description Cervical adenocarcinoma is the second most common histology of cervical cancer and treatment can involve surgery, radiotherapy, systemic therapy, and any combination of the three. Photon external beam radiation therapy and brachytherapy have been the mainstay of radiation treatment options for cervical cancer. Here, we report a case of a 41-year-old patient who had a prior renal transplant and was diagnosed with early-stage, intermediate-risk adenocarcinoma treated with modified radical hysterectomy plus adjuvant proton-beam therapy and vaginal brachytherapy. Treatment was well tolerated with a disease-free interval of 14-months and preserved renal function.
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publishDate 2024-12-01
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series Gynecologic Oncology Reports
spelling doaj-art-e26d73b9d1b04d3da74b8ab47f838c272025-08-20T02:37:45ZengElsevierGynecologic Oncology Reports2352-57892024-12-015610152010.1016/j.gore.2024.101520Novel use of adjuvant proton beam therapy in patient with pelvic renal transplant diagnosed with stage IB3 cervical adenocarcinomaPedro Versuti Del Cioppo Vasques0Jamie N. Bakkum-Gamez1Patrick G. Dean2Jeremy F. Molligan3Allison E. Garda4Mayo Clinic Alix School of Medicine, Rochester, MN, United States of AmericaDivision of Gynecologic Oncology Surgery, Mayo Clinic, Rochester, MN, United States of AmericaDivision of Transplantation Surgery, Mayo Clinic, Rochester, MN, United States of AmericaDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, United States of AmericaDepartment of Radiation Oncology, Mayo Clinic, Rochester, MN, United States of America; Corresponding author at: 200 First Street SW, Mayo Clinic, Rochester, MN 55905, United States of America.Cervical adenocarcinoma is the second most common histology of cervical cancer and treatment can involve surgery, radiotherapy, systemic therapy, and any combination of the three. Photon external beam radiation therapy and brachytherapy have been the mainstay of radiation treatment options for cervical cancer. Here, we report a case of a 41-year-old patient who had a prior renal transplant and was diagnosed with early-stage, intermediate-risk adenocarcinoma treated with modified radical hysterectomy plus adjuvant proton-beam therapy and vaginal brachytherapy. Treatment was well tolerated with a disease-free interval of 14-months and preserved renal function.http://www.sciencedirect.com/science/article/pii/S2352578924001991
spellingShingle Pedro Versuti Del Cioppo Vasques
Jamie N. Bakkum-Gamez
Patrick G. Dean
Jeremy F. Molligan
Allison E. Garda
Novel use of adjuvant proton beam therapy in patient with pelvic renal transplant diagnosed with stage IB3 cervical adenocarcinoma
Gynecologic Oncology Reports
title Novel use of adjuvant proton beam therapy in patient with pelvic renal transplant diagnosed with stage IB3 cervical adenocarcinoma
title_full Novel use of adjuvant proton beam therapy in patient with pelvic renal transplant diagnosed with stage IB3 cervical adenocarcinoma
title_fullStr Novel use of adjuvant proton beam therapy in patient with pelvic renal transplant diagnosed with stage IB3 cervical adenocarcinoma
title_full_unstemmed Novel use of adjuvant proton beam therapy in patient with pelvic renal transplant diagnosed with stage IB3 cervical adenocarcinoma
title_short Novel use of adjuvant proton beam therapy in patient with pelvic renal transplant diagnosed with stage IB3 cervical adenocarcinoma
title_sort novel use of adjuvant proton beam therapy in patient with pelvic renal transplant diagnosed with stage ib3 cervical adenocarcinoma
url http://www.sciencedirect.com/science/article/pii/S2352578924001991
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