Leiomyosarcoma Ex Pleomorphic Adenoma of the Parotid Gland: A Case Report and Literature Review
There is only one previously reported incident in the English literature of sarcoma ex pleomorphic adenoma of the parotid and there are only 8 cases of primary parotid leiomyosarcoma. In our case, a 79-year-old female patient presented to our care with left preauricular pain, swelling, and facial we...
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| Format: | Article |
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Wiley
2016-01-01
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| Series: | Case Reports in Otolaryngology |
| Online Access: | http://dx.doi.org/10.1155/2016/9795785 |
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| author | Michael Coulter Jingxuan Liu Mark Marzouk |
| author_facet | Michael Coulter Jingxuan Liu Mark Marzouk |
| author_sort | Michael Coulter |
| collection | DOAJ |
| description | There is only one previously reported incident in the English literature of sarcoma ex pleomorphic adenoma of the parotid and there are only 8 cases of primary parotid leiomyosarcoma. In our case, a 79-year-old female patient presented to our care with left preauricular pain, swelling, and facial weakness. After CT imaging, she underwent left total parotidectomy. A spindle cell lesion was identified intraoperatively and the facial nerve was sacrificed. Subsequent analysis of the lesion yielded a diagnosis of leiomyosarcoma ex pleomorphic adenoma. After 30 fractions of radiation therapy, scans were negative for tumor. However, 18 months after first experiencing symptoms, she was found to have metastases to the brainstem and lung. When diagnosing sarcoma ex pleomorphic adenoma of the parotid gland, it is important to perform thorough immunohistochemical staining and exclude a previous history of sarcoma or other sources of metastases. Complete resection is critical due to the tumor’s local aggressiveness and metastatic potential. Although these tumors are not very responsive to chemotherapy or radiation, adjuvant treatment is commonly used when margins are unclear. |
| format | Article |
| id | doaj-art-e2695fe05315480f834a36114aa3f790 |
| institution | Kabale University |
| issn | 2090-6765 2090-6773 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Otolaryngology |
| spelling | doaj-art-e2695fe05315480f834a36114aa3f7902025-02-03T01:30:09ZengWileyCase Reports in Otolaryngology2090-67652090-67732016-01-01201610.1155/2016/97957859795785Leiomyosarcoma Ex Pleomorphic Adenoma of the Parotid Gland: A Case Report and Literature ReviewMichael Coulter0Jingxuan Liu1Mark Marzouk2Health Science Center, Stony Brook University School of Medicine, Stony Brook, NY 11794, USADepartment of Pathology, Stony Brook University Hospital, 101 Nicolls Road, Stony Brook, NY 11794, USADepartment of Otolaryngology, Upstate University Hospital, 750 E. Adams, Syracuse, NY 13210, USAThere is only one previously reported incident in the English literature of sarcoma ex pleomorphic adenoma of the parotid and there are only 8 cases of primary parotid leiomyosarcoma. In our case, a 79-year-old female patient presented to our care with left preauricular pain, swelling, and facial weakness. After CT imaging, she underwent left total parotidectomy. A spindle cell lesion was identified intraoperatively and the facial nerve was sacrificed. Subsequent analysis of the lesion yielded a diagnosis of leiomyosarcoma ex pleomorphic adenoma. After 30 fractions of radiation therapy, scans were negative for tumor. However, 18 months after first experiencing symptoms, she was found to have metastases to the brainstem and lung. When diagnosing sarcoma ex pleomorphic adenoma of the parotid gland, it is important to perform thorough immunohistochemical staining and exclude a previous history of sarcoma or other sources of metastases. Complete resection is critical due to the tumor’s local aggressiveness and metastatic potential. Although these tumors are not very responsive to chemotherapy or radiation, adjuvant treatment is commonly used when margins are unclear.http://dx.doi.org/10.1155/2016/9795785 |
| spellingShingle | Michael Coulter Jingxuan Liu Mark Marzouk Leiomyosarcoma Ex Pleomorphic Adenoma of the Parotid Gland: A Case Report and Literature Review Case Reports in Otolaryngology |
| title | Leiomyosarcoma Ex Pleomorphic Adenoma of the Parotid Gland: A Case Report and Literature Review |
| title_full | Leiomyosarcoma Ex Pleomorphic Adenoma of the Parotid Gland: A Case Report and Literature Review |
| title_fullStr | Leiomyosarcoma Ex Pleomorphic Adenoma of the Parotid Gland: A Case Report and Literature Review |
| title_full_unstemmed | Leiomyosarcoma Ex Pleomorphic Adenoma of the Parotid Gland: A Case Report and Literature Review |
| title_short | Leiomyosarcoma Ex Pleomorphic Adenoma of the Parotid Gland: A Case Report and Literature Review |
| title_sort | leiomyosarcoma ex pleomorphic adenoma of the parotid gland a case report and literature review |
| url | http://dx.doi.org/10.1155/2016/9795785 |
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