LINC00162 silencing enhances sorafenib sensitivity and inhibits thyroid cancer cells progression through modulation of MAPK signaling and apoptosis

Abstract Many studies have reported the aberrant expression of lncRNAs and indicated their role in cancer progression and drug resistance across various cancers. In this study, we aimed to evaluate the effect of LINC00162 lncRNA on the chemosensitivity of thyroid cancer cells, both individually and...

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Main Authors: Maryam Hejazi, Seyedeh Zahra Bahojb Mahdavi, Saba Abedimanesh, Ramin Heshmat, Bagher Larijani, Amir Ali Mokhtarzadeh, Gita Shafiee, Seyed Mohammad Tavangar
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-12805-x
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