Prevalence of Nosocomial Venous Thromboembolic Complications in New Tuberculosis Patients and Relapses: Data from the Moscow City Registry (A Multicenter Study)

The objective: to evaluate VTEC in new tuberculosis patients and relapses, to determine main factors influencing its development (according to data of the patients admitted to Moscow tuberculosis hospitals)Subjects and Methods. Based on the data of epidemiological tuberculosis monitoring system of M...

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Main Authors: D. V. Plotkin, A. I. Titomer, K. V. Lobastov, M. N. Reshetnikov, M. V. Sinitsyn, R. V. Maltsev, N. O. Demchenkov, A. M. Abdurakhmanov, S. A. Sterlikov, E. M. Bogorodskaya
Format: Article
Language:Russian
Published: New Terra Publishing House 2024-03-01
Series:Туберкулез и болезни лёгких
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Online Access:https://www.tibl-journal.com/jour/article/view/1788
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author D. V. Plotkin
A. I. Titomer
K. V. Lobastov
M. N. Reshetnikov
M. V. Sinitsyn
R. V. Maltsev
N. O. Demchenkov
A. M. Abdurakhmanov
S. A. Sterlikov
E. M. Bogorodskaya
author_facet D. V. Plotkin
A. I. Titomer
K. V. Lobastov
M. N. Reshetnikov
M. V. Sinitsyn
R. V. Maltsev
N. O. Demchenkov
A. M. Abdurakhmanov
S. A. Sterlikov
E. M. Bogorodskaya
author_sort D. V. Plotkin
collection DOAJ
description The objective: to evaluate VTEC in new tuberculosis patients and relapses, to determine main factors influencing its development (according to data of the patients admitted to Moscow tuberculosis hospitals)Subjects and Methods. Based on the data of epidemiological tuberculosis monitoring system of Moscow, treatment outcomes of 4609 tuberculosis patients admitted to tuberculosis hospitals from 2020 to 2022 were retrospectively analyzed. The incidence of VTEC was estimated.Results. Totally 214/4609 cases of VTEC were identified (4.6%; 95% CI 4.1-5.3%), among which the incidence of DVT made 3.5% (95% CI 3.0-4.1%), SVP 1.5% (95% CI 1.2-1.9%), and PATE 0.6% (95% CI 0.4-0.8%). The most significant risk factors of thrombotic complications in tuberculosis patients were identified, those factors included HIV infection (RR 3.8; 95% CI 2.7-4.5) and fibrous cavernous form of pulmonary tuberculosis (RR 9.1; 95% CI 4.7-17.6). The overall prevalence of VTEC in tuberculosis hospitals was 3 or more times higher than in general clinics (according to the published data).Conclusion. The data obtained indicate that patients hospitalized for pulmonary tuberculosis face a high risk of VTEC development that requires prediction and prevention.
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series Туберкулез и болезни лёгких
spelling doaj-art-e23480096a1642eeadaa6c879f6f7c732025-08-20T01:47:41ZrusNew Terra Publishing HouseТуберкулез и болезни лёгких2075-12302542-15062024-03-011021121910.58838/2075-1230-2024-102-1-12-191783Prevalence of Nosocomial Venous Thromboembolic Complications in New Tuberculosis Patients and Relapses: Data from the Moscow City Registry (A Multicenter Study)D. V. Plotkin0A. I. Titomer1K. V. Lobastov2M. N. Reshetnikov3M. V. Sinitsyn4R. V. Maltsev5N. O. Demchenkov6A. M. Abdurakhmanov7S. A. Sterlikov8E. M. Bogorodskaya9Moscow Research and Clinical Center for Tuberculosis Control of the Moscow Government Department of Health; Pirogov Russian National Research Medical University, Russian Ministry of HealthMoscow Research and Clinical Center for Tuberculosis Control of the Moscow Government Department of HealthPirogov Russian National Research Medical University, Russian Ministry of HealthMoscow Research and Clinical Center for Tuberculosis Control of the Moscow Government Department of Health; Russian Medical Academy of On-going Professional Education, Russian Ministry of HealthPirogov Russian National Research Medical University, Russian Ministry of HealthG.A. Zakharyin Tuberculosis Clinical Hospital no.3, Moscow Health DepartmentPirogov Russian National Research Medical University, Russian Ministry of HealthA.E. Rabukhin Tuberculosis Hospital, Moscow Health DepartmentRussian Research Institute of Health, Russian Ministry of HealthMoscow Research and Clinical Center for Tuberculosis Control of the Moscow Government Department of Health; Russian Medical Academy of On-going Professional Education, Russian Ministry of HealthThe objective: to evaluate VTEC in new tuberculosis patients and relapses, to determine main factors influencing its development (according to data of the patients admitted to Moscow tuberculosis hospitals)Subjects and Methods. Based on the data of epidemiological tuberculosis monitoring system of Moscow, treatment outcomes of 4609 tuberculosis patients admitted to tuberculosis hospitals from 2020 to 2022 were retrospectively analyzed. The incidence of VTEC was estimated.Results. Totally 214/4609 cases of VTEC were identified (4.6%; 95% CI 4.1-5.3%), among which the incidence of DVT made 3.5% (95% CI 3.0-4.1%), SVP 1.5% (95% CI 1.2-1.9%), and PATE 0.6% (95% CI 0.4-0.8%). The most significant risk factors of thrombotic complications in tuberculosis patients were identified, those factors included HIV infection (RR 3.8; 95% CI 2.7-4.5) and fibrous cavernous form of pulmonary tuberculosis (RR 9.1; 95% CI 4.7-17.6). The overall prevalence of VTEC in tuberculosis hospitals was 3 or more times higher than in general clinics (according to the published data).Conclusion. The data obtained indicate that patients hospitalized for pulmonary tuberculosis face a high risk of VTEC development that requires prediction and prevention.https://www.tibl-journal.com/jour/article/view/1788venous thrombosistuberculosisthromboembolismhivhypercoagulation
spellingShingle D. V. Plotkin
A. I. Titomer
K. V. Lobastov
M. N. Reshetnikov
M. V. Sinitsyn
R. V. Maltsev
N. O. Demchenkov
A. M. Abdurakhmanov
S. A. Sterlikov
E. M. Bogorodskaya
Prevalence of Nosocomial Venous Thromboembolic Complications in New Tuberculosis Patients and Relapses: Data from the Moscow City Registry (A Multicenter Study)
Туберкулез и болезни лёгких
venous thrombosis
tuberculosis
thromboembolism
hiv
hypercoagulation
title Prevalence of Nosocomial Venous Thromboembolic Complications in New Tuberculosis Patients and Relapses: Data from the Moscow City Registry (A Multicenter Study)
title_full Prevalence of Nosocomial Venous Thromboembolic Complications in New Tuberculosis Patients and Relapses: Data from the Moscow City Registry (A Multicenter Study)
title_fullStr Prevalence of Nosocomial Venous Thromboembolic Complications in New Tuberculosis Patients and Relapses: Data from the Moscow City Registry (A Multicenter Study)
title_full_unstemmed Prevalence of Nosocomial Venous Thromboembolic Complications in New Tuberculosis Patients and Relapses: Data from the Moscow City Registry (A Multicenter Study)
title_short Prevalence of Nosocomial Venous Thromboembolic Complications in New Tuberculosis Patients and Relapses: Data from the Moscow City Registry (A Multicenter Study)
title_sort prevalence of nosocomial venous thromboembolic complications in new tuberculosis patients and relapses data from the moscow city registry a multicenter study
topic venous thrombosis
tuberculosis
thromboembolism
hiv
hypercoagulation
url https://www.tibl-journal.com/jour/article/view/1788
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