An overview of AI in Biofunctional Materials

The integration of artificial intelligence (AI) into biofunctional materials is transforming material design, synthesis, and optimization for medical applications. Machine learning and deep learning models now predict material properties (e.g., mechanical strength, degradation rate) with > 90% ac...

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Main Author: Dazhou Li
Format: Article
Language:English
Published: ELS Publishing (ELSP) 2025-06-01
Series:Biofunctional Materials
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Online Access:https://elsp-homepage.oss-cn-hongkong.aliyuncs.compaper/journal/open/BM/2025/bm20250010.pdf
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author Dazhou Li
author_facet Dazhou Li
author_sort Dazhou Li
collection DOAJ
description The integration of artificial intelligence (AI) into biofunctional materials is transforming material design, synthesis, and optimization for medical applications. Machine learning and deep learning models now predict material properties (e.g., mechanical strength, degradation rate) with > 90% accuracy, dramatically reducing trial-and-error in scaffold and nanoparticle fabrication. AI-driven platforms accelerate surface functionalization strategies to enhance cell adhesion and drug loading, while generative models design stimuli-responsive hydrogels and smart polymers that mimic tissue mechanics. Case studies include rapid optimization of nanoparticle synthesis via Bayesian frameworks and the discovery of biodegradable stent materials through random forest screening. Despite remaining challenges in data quality and regulatory alignment, these advances underscore AI’s capacity to deliver high-performance, sustainable biomaterials and point toward an interdisciplinary roadmap for next-generation therapeutic solutions.
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publisher ELS Publishing (ELSP)
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series Biofunctional Materials
spelling doaj-art-e22f5e4bb9f949c1a2b0a8bc3dde23b72025-08-20T03:07:28ZengELS Publishing (ELSP)Biofunctional Materials2959-05742959-05822025-06-013210.55092/bm202500101888399749320298496An overview of AI in Biofunctional MaterialsDazhou Li0College of Computer Science and Technology, Shenyang University of Chemical Technology, Shenyang, ChinaThe integration of artificial intelligence (AI) into biofunctional materials is transforming material design, synthesis, and optimization for medical applications. Machine learning and deep learning models now predict material properties (e.g., mechanical strength, degradation rate) with > 90% accuracy, dramatically reducing trial-and-error in scaffold and nanoparticle fabrication. AI-driven platforms accelerate surface functionalization strategies to enhance cell adhesion and drug loading, while generative models design stimuli-responsive hydrogels and smart polymers that mimic tissue mechanics. Case studies include rapid optimization of nanoparticle synthesis via Bayesian frameworks and the discovery of biodegradable stent materials through random forest screening. Despite remaining challenges in data quality and regulatory alignment, these advances underscore AI’s capacity to deliver high-performance, sustainable biomaterials and point toward an interdisciplinary roadmap for next-generation therapeutic solutions.https://elsp-homepage.oss-cn-hongkong.aliyuncs.compaper/journal/open/BM/2025/bm20250010.pdfai in biofunctional materialsmachine learning in material designbiomaterials in tissue engineeringbiocompatible materialssustainable biomaterialsdata-driven material optimization
spellingShingle Dazhou Li
An overview of AI in Biofunctional Materials
Biofunctional Materials
ai in biofunctional materials
machine learning in material design
biomaterials in tissue engineering
biocompatible materials
sustainable biomaterials
data-driven material optimization
title An overview of AI in Biofunctional Materials
title_full An overview of AI in Biofunctional Materials
title_fullStr An overview of AI in Biofunctional Materials
title_full_unstemmed An overview of AI in Biofunctional Materials
title_short An overview of AI in Biofunctional Materials
title_sort overview of ai in biofunctional materials
topic ai in biofunctional materials
machine learning in material design
biomaterials in tissue engineering
biocompatible materials
sustainable biomaterials
data-driven material optimization
url https://elsp-homepage.oss-cn-hongkong.aliyuncs.compaper/journal/open/BM/2025/bm20250010.pdf
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