Radiological Screening of Atlantoaxial Instability in Children with Trisomy 21: A Systematic Review and Evidence-Based Recommendations

Radiological Screening of Atlantoaxial Instability in Children with Trisomy 21: A Systematic Review and Evidence-Based Recommendations

<b>Background/Objectives</b>: Atlantoaxial instability (AAI) affects approximately 20% of individuals with Trisomy 21. Radiological screening has been debated for decades due to its unclear clinical utility and lack of standardized diagnostic criteria. This systematic review evaluates th...

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Bibliographic Details
Main Authors: Leo Cattarinussi, Aline Bregou, Christopher J. Newman, Sophie R. Merckaert
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Children
Subjects:
Down syndrome
Trisomy 21
atlantoaxial instability
cervical spine
Online Access:https://www.mdpi.com/2227-9067/12/4/421
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