Hepatocellular Carcinoma to the Right Ventricle

Hepatocellular carcinoma (HCC) is the sixth most prevalent cancer in the world, but metastatic disease to the heart is rare. We present a case of a 63-year-old man with history of hepatitis C and cirrhosis, which had progressed to HCC. The patient had undergone two prior liver transplantations. He p...

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Main Authors: George R. Marzouka, Apurva Badheka, Alexis P. Rodriguez, Sandra V. Chaparro
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Case Reports in Cardiology
Online Access:http://dx.doi.org/10.1155/2014/192737
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author George R. Marzouka
Apurva Badheka
Alexis P. Rodriguez
Sandra V. Chaparro
author_facet George R. Marzouka
Apurva Badheka
Alexis P. Rodriguez
Sandra V. Chaparro
author_sort George R. Marzouka
collection DOAJ
description Hepatocellular carcinoma (HCC) is the sixth most prevalent cancer in the world, but metastatic disease to the heart is rare. We present a case of a 63-year-old man with history of hepatitis C and cirrhosis, which had progressed to HCC. The patient had undergone two prior liver transplantations. He presented to the hospital complaining of worsening lower extremity edema. His exam was also pertinent for jugular venous distension, a 3/6 crescendo-decrescendo murmur, and hepatosplenomegaly. A transthoracic echocardiogram showed a large irregular lobulated mass in the apex of the right ventricle with a mobile pedunculated component. An MRI of the heart revealed a 4.4 × 3.4 × 4.0 cm mass within the right ventricular apex, which was subsequently biopsied and found to be moderately differentiated HCC with myocardial fragments. The patient opted out of any further therapy, or intervention, and was enrolled in hospice care.
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spelling doaj-art-e21cf22da63c429db2404c723fcdc6d82025-02-03T05:58:18ZengWileyCase Reports in Cardiology2090-64042090-64122014-01-01201410.1155/2014/192737192737Hepatocellular Carcinoma to the Right VentricleGeorge R. Marzouka0Apurva Badheka1Alexis P. Rodriguez2Sandra V. Chaparro3Division of Cardiology, University of Miami Miller School of Medicine, 1120 NW 14th Street, Clinical Research Building, Room 1107, Miami, FL 33136, USADivision of Cardiology, University of Miami Miller School of Medicine, 1120 NW 14th Street, Clinical Research Building, Room 1107, Miami, FL 33136, USADepartment of Internal Medicine, University of Miami Miller School of Medicine, 1611 NW 12th Avenue, Central Building, Room 600D, Miami, FL 33136, USADivision of Cardiology, University of Miami Miller School of Medicine, 1120 NW 14th Street, Clinical Research Building, Room 1107, Miami, FL 33136, USAHepatocellular carcinoma (HCC) is the sixth most prevalent cancer in the world, but metastatic disease to the heart is rare. We present a case of a 63-year-old man with history of hepatitis C and cirrhosis, which had progressed to HCC. The patient had undergone two prior liver transplantations. He presented to the hospital complaining of worsening lower extremity edema. His exam was also pertinent for jugular venous distension, a 3/6 crescendo-decrescendo murmur, and hepatosplenomegaly. A transthoracic echocardiogram showed a large irregular lobulated mass in the apex of the right ventricle with a mobile pedunculated component. An MRI of the heart revealed a 4.4 × 3.4 × 4.0 cm mass within the right ventricular apex, which was subsequently biopsied and found to be moderately differentiated HCC with myocardial fragments. The patient opted out of any further therapy, or intervention, and was enrolled in hospice care.http://dx.doi.org/10.1155/2014/192737
spellingShingle George R. Marzouka
Apurva Badheka
Alexis P. Rodriguez
Sandra V. Chaparro
Hepatocellular Carcinoma to the Right Ventricle
Case Reports in Cardiology
title Hepatocellular Carcinoma to the Right Ventricle
title_full Hepatocellular Carcinoma to the Right Ventricle
title_fullStr Hepatocellular Carcinoma to the Right Ventricle
title_full_unstemmed Hepatocellular Carcinoma to the Right Ventricle
title_short Hepatocellular Carcinoma to the Right Ventricle
title_sort hepatocellular carcinoma to the right ventricle
url http://dx.doi.org/10.1155/2014/192737
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AT apurvabadheka hepatocellularcarcinomatotherightventricle
AT alexisprodriguez hepatocellularcarcinomatotherightventricle
AT sandravchaparro hepatocellularcarcinomatotherightventricle