Predictive value of machine learning for the progression of gestational diabetes mellitus to type 2 diabetes: a systematic review and meta-analysis

Abstract Background This systematic review aims to explore the early predictive value of machine learning (ML) models for the progression of gestational diabetes mellitus (GDM) to type 2 diabetes mellitus (T2DM). Methods A comprehensive and systematic search was conducted in Pubmed, Cochrane, Embase...

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Main Authors: Meng Zhao, Zhixin Yao, Yan Zhang, Lidan Ma, Wenquan Pang, Shuyin Ma, Yijun Xu, Lili Wei
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Medical Informatics and Decision Making
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Online Access:https://doi.org/10.1186/s12911-024-02848-x
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author Meng Zhao
Zhixin Yao
Yan Zhang
Lidan Ma
Wenquan Pang
Shuyin Ma
Yijun Xu
Lili Wei
author_facet Meng Zhao
Zhixin Yao
Yan Zhang
Lidan Ma
Wenquan Pang
Shuyin Ma
Yijun Xu
Lili Wei
author_sort Meng Zhao
collection DOAJ
description Abstract Background This systematic review aims to explore the early predictive value of machine learning (ML) models for the progression of gestational diabetes mellitus (GDM) to type 2 diabetes mellitus (T2DM). Methods A comprehensive and systematic search was conducted in Pubmed, Cochrane, Embase, and Web of Science up to July 02, 2024. The quality of the studies included was assessed. The risk of bias was assessed through the prediction model risk of bias assessment tool and a graph was drawn accordingly. The meta-analysis was performed using Stata15.0. Results A total of 13 studies were included in the present review, involving 11,320 GDM patients and 22 ML models. The meta-analysis for ML models showed a pooled C-statistic of 0.82 (95% CI: 0.79 ~ 0.86), a pooled sensitivity of 0.76 (0.72 ~ 0.80), and a pooled specificity of 0.57 (0.50 ~ 0.65). Conclusion ML has favorable diagnostic accuracy for the progression of GDM to T2DM. This provides evidence for the development of predictive tools with broader applicability.
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spelling doaj-art-e21aa8df010347eb85cb25d015e29e702025-01-19T12:26:00ZengBMCBMC Medical Informatics and Decision Making1472-69472025-01-0125111010.1186/s12911-024-02848-xPredictive value of machine learning for the progression of gestational diabetes mellitus to type 2 diabetes: a systematic review and meta-analysisMeng Zhao0Zhixin Yao1Yan Zhang2Lidan Ma3Wenquan Pang4Shuyin Ma5Yijun Xu6Lili Wei7Department of Endocrinology and Metabolic Diseases, The Affiliated Hospital of Medical College Qingdao UniversityDepartment of Endocrinology and Metabolic Diseases, The Affiliated Hospital of Medical College Qingdao UniversityDepartment of Endocrinology and Metabolic Diseases, The Affiliated Hospital of Medical College Qingdao UniversityDepartment of Endocrinology and Metabolic Diseases, The Affiliated Hospital of Medical College Qingdao UniversityDepartment of Endocrinology and Metabolic Diseases, The Affiliated Hospital of Medical College Qingdao UniversityDepartment of Emergency Pediatric, The Affiliated Hospital of Medical College Qingdao UniversityDepartment of Endocrinology and Metabolic Diseases, The Affiliated Hospital of Medical College Qingdao UniversityDepartment of Nursing, The Affiliated Hospital of Medical College Qingdao UniversityAbstract Background This systematic review aims to explore the early predictive value of machine learning (ML) models for the progression of gestational diabetes mellitus (GDM) to type 2 diabetes mellitus (T2DM). Methods A comprehensive and systematic search was conducted in Pubmed, Cochrane, Embase, and Web of Science up to July 02, 2024. The quality of the studies included was assessed. The risk of bias was assessed through the prediction model risk of bias assessment tool and a graph was drawn accordingly. The meta-analysis was performed using Stata15.0. Results A total of 13 studies were included in the present review, involving 11,320 GDM patients and 22 ML models. The meta-analysis for ML models showed a pooled C-statistic of 0.82 (95% CI: 0.79 ~ 0.86), a pooled sensitivity of 0.76 (0.72 ~ 0.80), and a pooled specificity of 0.57 (0.50 ~ 0.65). Conclusion ML has favorable diagnostic accuracy for the progression of GDM to T2DM. This provides evidence for the development of predictive tools with broader applicability.https://doi.org/10.1186/s12911-024-02848-xClinical prediction modelGestational diabetes mellitusMachine learningType 2 diabetes mellitusSystematic review
spellingShingle Meng Zhao
Zhixin Yao
Yan Zhang
Lidan Ma
Wenquan Pang
Shuyin Ma
Yijun Xu
Lili Wei
Predictive value of machine learning for the progression of gestational diabetes mellitus to type 2 diabetes: a systematic review and meta-analysis
BMC Medical Informatics and Decision Making
Clinical prediction model
Gestational diabetes mellitus
Machine learning
Type 2 diabetes mellitus
Systematic review
title Predictive value of machine learning for the progression of gestational diabetes mellitus to type 2 diabetes: a systematic review and meta-analysis
title_full Predictive value of machine learning for the progression of gestational diabetes mellitus to type 2 diabetes: a systematic review and meta-analysis
title_fullStr Predictive value of machine learning for the progression of gestational diabetes mellitus to type 2 diabetes: a systematic review and meta-analysis
title_full_unstemmed Predictive value of machine learning for the progression of gestational diabetes mellitus to type 2 diabetes: a systematic review and meta-analysis
title_short Predictive value of machine learning for the progression of gestational diabetes mellitus to type 2 diabetes: a systematic review and meta-analysis
title_sort predictive value of machine learning for the progression of gestational diabetes mellitus to type 2 diabetes a systematic review and meta analysis
topic Clinical prediction model
Gestational diabetes mellitus
Machine learning
Type 2 diabetes mellitus
Systematic review
url https://doi.org/10.1186/s12911-024-02848-x
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