Deterioration in Clinical Status Is Not Enough to Suspend Eculizumab: A Genetic Complement-Mediated Atypical Hemolytic Uremic Syndrome Case Report

Deterioration in Clinical Status Is Not Enough to Suspend Eculizumab: A Genetic Complement-Mediated Atypical Hemolytic Uremic Syndrome Case Report

Background. Atypical hemolytic uremic syndrome (aHUS) is characterized by microangiopathic hemolytic anemia, thrombocytopenia, and renal failure. Mutations in CFI gene coding for complement regulation factors and in THBD gene coding for endothelial cell receptor thrombomodulin could predispose to th...

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Bibliographic Details
Main Authors: Luca Calvaruso, Alessandro Naticchia, Pietro Manuel Ferraro, Gisella Vischini, Stefano Costanzi
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Case Reports in Nephrology
Online Access:http://dx.doi.org/10.1155/2019/9264824
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