Olanzapine: The game-changer “antiemetic”

Chemotherapy-induced nausea and vomiting (CINV) is significantly debilitating and worsens the quality of life. Olanzapine, an atypical antipsychotic drug, also has an antiemetic potential. Studies have shown that olanzapine-based regimens have similar efficacy as compared to aprepitant in patients r...

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Main Author: Manikandan Dhanushkodi
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2019-01-01
Series:Indian Journal of Medical and Paediatric Oncology
Subjects:
Online Access:http://www.ijmpo.org/article.asp?issn=0971-5851;year=2019;volume=40;issue=2;spage=274;epage=276;aulast=Dhanushkodi
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author Manikandan Dhanushkodi
author_facet Manikandan Dhanushkodi
author_sort Manikandan Dhanushkodi
collection DOAJ
description Chemotherapy-induced nausea and vomiting (CINV) is significantly debilitating and worsens the quality of life. Olanzapine, an atypical antipsychotic drug, also has an antiemetic potential. Studies have shown that olanzapine-based regimens have similar efficacy as compared to aprepitant in patients receiving highly emetogenic chemotherapy (HEC). National Comprehensive Cancer Network guidelines also recommends olanzapine-based regimen in HEC. Olanzapine, palonosetron, dexamethasone regimen is a cost-effective option in resource-limited settings in patients receiving HEC.
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publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
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series Indian Journal of Medical and Paediatric Oncology
spelling doaj-art-e1fe69a4a3d24e46a5e1cf70c2aee3f42025-08-20T01:55:52ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Medical and Paediatric Oncology0971-58510975-21292019-01-0140227427610.4103/ijmpo.ijmpo_151_19Olanzapine: The game-changer “antiemetic”Manikandan DhanushkodiChemotherapy-induced nausea and vomiting (CINV) is significantly debilitating and worsens the quality of life. Olanzapine, an atypical antipsychotic drug, also has an antiemetic potential. Studies have shown that olanzapine-based regimens have similar efficacy as compared to aprepitant in patients receiving highly emetogenic chemotherapy (HEC). National Comprehensive Cancer Network guidelines also recommends olanzapine-based regimen in HEC. Olanzapine, palonosetron, dexamethasone regimen is a cost-effective option in resource-limited settings in patients receiving HEC.http://www.ijmpo.org/article.asp?issn=0971-5851;year=2019;volume=40;issue=2;spage=274;epage=276;aulast=Dhanushkodichemotherapy-induced nausea and vomitinghighly emetogenic chemotherapyolanzapine
spellingShingle Manikandan Dhanushkodi
Olanzapine: The game-changer “antiemetic”
Indian Journal of Medical and Paediatric Oncology
chemotherapy-induced nausea and vomiting
highly emetogenic chemotherapy
olanzapine
title Olanzapine: The game-changer “antiemetic”
title_full Olanzapine: The game-changer “antiemetic”
title_fullStr Olanzapine: The game-changer “antiemetic”
title_full_unstemmed Olanzapine: The game-changer “antiemetic”
title_short Olanzapine: The game-changer “antiemetic”
title_sort olanzapine the game changer antiemetic
topic chemotherapy-induced nausea and vomiting
highly emetogenic chemotherapy
olanzapine
url http://www.ijmpo.org/article.asp?issn=0971-5851;year=2019;volume=40;issue=2;spage=274;epage=276;aulast=Dhanushkodi
work_keys_str_mv AT manikandandhanushkodi olanzapinethegamechangerantiemetic