Adolescent with Rhabdomyolysis due to Undiagnosed Hypothyroidism
Exercise-induced rhabdomyolysis has been described in military recruits, trained athletes and daily runners. Statin use, quail ingestion, infection by Epstein-Barr virus (EBV), and hypothyroidism, though rare, are risk factors for the development of rhabdomyolysis. We describe the case of a 15-year-...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Case Reports in Pediatrics |
| Online Access: | http://dx.doi.org/10.1155/2011/670673 |
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| author | Raquel Farias Moeller Nassim Zecavati Rosa Sherafat-Kazemzadeh Shoshana Aleinikoff Wolfgang Rennert |
| author_facet | Raquel Farias Moeller Nassim Zecavati Rosa Sherafat-Kazemzadeh Shoshana Aleinikoff Wolfgang Rennert |
| author_sort | Raquel Farias Moeller |
| collection | DOAJ |
| description | Exercise-induced rhabdomyolysis has been described in military recruits, trained athletes and daily runners. Statin use, quail ingestion, infection by Epstein-Barr virus (EBV), and hypothyroidism, though rare, are risk factors for the development of rhabdomyolysis. We describe the case of a 15-year-old female who presented with myalgias, weakness, and pigmenturia following marching band practice. Laboratory tests confirmed an elevated creatine kinase (CK) level as well as a profound hypothyroid state. Muscle biopsy revealed severe muscle necrosis and myositis. Treatment with levothyroxine resulted in obtaining an euthyroid state and regain of muscle strength as well as decrease in CK levels. Although rare, hypothyroidism should be considered as a potential cause of rhabdomyolysis in pediatric patients undergoing a myopathy workup. |
| format | Article |
| id | doaj-art-e1fb9771d7bd4eeaae461c5b0063ee5d |
| institution | Kabale University |
| issn | 2090-6803 2090-6811 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pediatrics |
| spelling | doaj-art-e1fb9771d7bd4eeaae461c5b0063ee5d2025-02-03T05:44:29ZengWileyCase Reports in Pediatrics2090-68032090-68112011-01-01201110.1155/2011/670673670673Adolescent with Rhabdomyolysis due to Undiagnosed HypothyroidismRaquel Farias Moeller0Nassim Zecavati1Rosa Sherafat-Kazemzadeh2Shoshana Aleinikoff3Wolfgang Rennert4Department of Pediatrics, Georgetown University Hospital Medical Center, Washington, DC, USADivision of Neurology, Georgetown University Hospital Medical Center, Washington, DC, USADivision of Endocrinology and Metabolism, Georgetown University Hospital Medical Center, Washington, DC, USADepartment of Pediatrics, Georgetown University Hospital Medical Center, Washington, DC, USADepartment of Pediatrics, Georgetown University Hospital Medical Center, Washington, DC, USAExercise-induced rhabdomyolysis has been described in military recruits, trained athletes and daily runners. Statin use, quail ingestion, infection by Epstein-Barr virus (EBV), and hypothyroidism, though rare, are risk factors for the development of rhabdomyolysis. We describe the case of a 15-year-old female who presented with myalgias, weakness, and pigmenturia following marching band practice. Laboratory tests confirmed an elevated creatine kinase (CK) level as well as a profound hypothyroid state. Muscle biopsy revealed severe muscle necrosis and myositis. Treatment with levothyroxine resulted in obtaining an euthyroid state and regain of muscle strength as well as decrease in CK levels. Although rare, hypothyroidism should be considered as a potential cause of rhabdomyolysis in pediatric patients undergoing a myopathy workup.http://dx.doi.org/10.1155/2011/670673 |
| spellingShingle | Raquel Farias Moeller Nassim Zecavati Rosa Sherafat-Kazemzadeh Shoshana Aleinikoff Wolfgang Rennert Adolescent with Rhabdomyolysis due to Undiagnosed Hypothyroidism Case Reports in Pediatrics |
| title | Adolescent with Rhabdomyolysis due to Undiagnosed Hypothyroidism |
| title_full | Adolescent with Rhabdomyolysis due to Undiagnosed Hypothyroidism |
| title_fullStr | Adolescent with Rhabdomyolysis due to Undiagnosed Hypothyroidism |
| title_full_unstemmed | Adolescent with Rhabdomyolysis due to Undiagnosed Hypothyroidism |
| title_short | Adolescent with Rhabdomyolysis due to Undiagnosed Hypothyroidism |
| title_sort | adolescent with rhabdomyolysis due to undiagnosed hypothyroidism |
| url | http://dx.doi.org/10.1155/2011/670673 |
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