Investigation of Charge Transfer Complexes Formed between Mirtazapine and Some π-Acceptors
Charge transfer complexes (CTC) of mirtazapine with tetracyanoethylene (TCNE), 2,3-dichloro-5,6-dicyano-p-benzoquinone (DDQ), and tetracyanoquinodimethane (TCNQ) have been studied spectrophotometrically in dichloromethane at room temperature. The stoichiometries of the complexes were found to be 1 :...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Journal of Spectroscopy |
| Online Access: | http://dx.doi.org/10.1155/2013/875953 |
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| author | Hulya Demirhan Mustafa Arslan Mustafa Zengin Mustafa Kucukislamoglu |
| author_facet | Hulya Demirhan Mustafa Arslan Mustafa Zengin Mustafa Kucukislamoglu |
| author_sort | Hulya Demirhan |
| collection | DOAJ |
| description | Charge transfer complexes (CTC) of mirtazapine with tetracyanoethylene (TCNE), 2,3-dichloro-5,6-dicyano-p-benzoquinone (DDQ), and tetracyanoquinodimethane (TCNQ) have been studied spectrophotometrically in dichloromethane at room temperature. The stoichiometries of the complexes were found to be 1 : 1 ratio by the Job Method between mirtazapine and the acceptors. The equilibrium constants and thermodynamic parameters of the complexes were determined by the Benesi-Hildebrand and Van't Hoff equations. Mirtazapine in pure and dosage form was applied in this study. The results indicate that the formation constants for the complexes depend on the nature of electron acceptors and donor. And also the spectral studies of the complexes were determined by FT-IR and NMR spectroscopy. |
| format | Article |
| id | doaj-art-e1f151fb67204e1b903031d883fac1e9 |
| institution | Kabale University |
| issn | 2314-4920 2314-4939 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Spectroscopy |
| spelling | doaj-art-e1f151fb67204e1b903031d883fac1e92025-02-03T06:44:23ZengWileyJournal of Spectroscopy2314-49202314-49392013-01-01201310.1155/2013/875953875953Investigation of Charge Transfer Complexes Formed between Mirtazapine and Some π-AcceptorsHulya Demirhan0Mustafa Arslan1Mustafa Zengin2Mustafa Kucukislamoglu3Chemistry Department, Faculty of Arts and Sciences, Sakarya University, 54187 Sakarya, TurkeyChemistry Department, Faculty of Arts and Sciences, Sakarya University, 54187 Sakarya, TurkeyChemistry Department, Faculty of Arts and Sciences, Sakarya University, 54187 Sakarya, TurkeyChemistry Department, Faculty of Arts and Sciences, Sakarya University, 54187 Sakarya, TurkeyCharge transfer complexes (CTC) of mirtazapine with tetracyanoethylene (TCNE), 2,3-dichloro-5,6-dicyano-p-benzoquinone (DDQ), and tetracyanoquinodimethane (TCNQ) have been studied spectrophotometrically in dichloromethane at room temperature. The stoichiometries of the complexes were found to be 1 : 1 ratio by the Job Method between mirtazapine and the acceptors. The equilibrium constants and thermodynamic parameters of the complexes were determined by the Benesi-Hildebrand and Van't Hoff equations. Mirtazapine in pure and dosage form was applied in this study. The results indicate that the formation constants for the complexes depend on the nature of electron acceptors and donor. And also the spectral studies of the complexes were determined by FT-IR and NMR spectroscopy.http://dx.doi.org/10.1155/2013/875953 |
| spellingShingle | Hulya Demirhan Mustafa Arslan Mustafa Zengin Mustafa Kucukislamoglu Investigation of Charge Transfer Complexes Formed between Mirtazapine and Some π-Acceptors Journal of Spectroscopy |
| title | Investigation of Charge Transfer Complexes Formed between Mirtazapine and Some π-Acceptors |
| title_full | Investigation of Charge Transfer Complexes Formed between Mirtazapine and Some π-Acceptors |
| title_fullStr | Investigation of Charge Transfer Complexes Formed between Mirtazapine and Some π-Acceptors |
| title_full_unstemmed | Investigation of Charge Transfer Complexes Formed between Mirtazapine and Some π-Acceptors |
| title_short | Investigation of Charge Transfer Complexes Formed between Mirtazapine and Some π-Acceptors |
| title_sort | investigation of charge transfer complexes formed between mirtazapine and some π acceptors |
| url | http://dx.doi.org/10.1155/2013/875953 |
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