Therapeutic Potential of Dietary Phenolic Acids

Although modern lifestyle has eased the quality of human life, this lifestyle’s related patterns have imparted negative effects on health to acquire multiple diseases. Many synthetic drugs are invented during the last millennium but most if not all of them possess several side effects and proved to...

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Main Authors: Venkata Saibabu, Zeeshan Fatima, Luqman Ahmad Khan, Saif Hameed
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Advances in Pharmacological Sciences
Online Access:http://dx.doi.org/10.1155/2015/823539
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author Venkata Saibabu
Zeeshan Fatima
Luqman Ahmad Khan
Saif Hameed
author_facet Venkata Saibabu
Zeeshan Fatima
Luqman Ahmad Khan
Saif Hameed
author_sort Venkata Saibabu
collection DOAJ
description Although modern lifestyle has eased the quality of human life, this lifestyle’s related patterns have imparted negative effects on health to acquire multiple diseases. Many synthetic drugs are invented during the last millennium but most if not all of them possess several side effects and proved to be costly. Convincing evidences have established the premise that the phytotherapeutic potential of natural compounds and need of search for novel drugs from natural sources are of high priority. Phenolic acids (PAs) are a class of secondary metabolites spread throughout the plant kingdom and generally involved in plethora of cellular processes involved in plant growth and reproduction and also produced as defense mechanism to sustain various environmental stresses. Extensive research on PAs strongly suggests that consumption of these compounds hold promise to offer protection against various ailments in humans. This paper focuses on the naturally derived PAs and summarizes the action mechanisms of these compounds during disease conditions. Based on the available information in the literature, it is suggested that use of PAs as drugs is very promising; however more research and clinical trials are necessary before these bioactive molecules can be made for treatment. Finally this review provides greater awareness of the promise that natural PAs hold for use in the disease prevention and therapy.
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spelling doaj-art-e1eaa9ac77544275a72ea261fbcdc9622025-02-03T01:24:12ZengWileyAdvances in Pharmacological Sciences1687-63341687-63422015-01-01201510.1155/2015/823539823539Therapeutic Potential of Dietary Phenolic AcidsVenkata Saibabu0Zeeshan Fatima1Luqman Ahmad Khan2Saif Hameed3Amity Institute of Biotechnology, Amity University Haryana, Gurgaon, Manesar 122413, IndiaAmity Institute of Biotechnology, Amity University Haryana, Gurgaon, Manesar 122413, IndiaDepartment of Biosciences, Jamia Millia Islamia, New Delhi 110025, IndiaAmity Institute of Biotechnology, Amity University Haryana, Gurgaon, Manesar 122413, IndiaAlthough modern lifestyle has eased the quality of human life, this lifestyle’s related patterns have imparted negative effects on health to acquire multiple diseases. Many synthetic drugs are invented during the last millennium but most if not all of them possess several side effects and proved to be costly. Convincing evidences have established the premise that the phytotherapeutic potential of natural compounds and need of search for novel drugs from natural sources are of high priority. Phenolic acids (PAs) are a class of secondary metabolites spread throughout the plant kingdom and generally involved in plethora of cellular processes involved in plant growth and reproduction and also produced as defense mechanism to sustain various environmental stresses. Extensive research on PAs strongly suggests that consumption of these compounds hold promise to offer protection against various ailments in humans. This paper focuses on the naturally derived PAs and summarizes the action mechanisms of these compounds during disease conditions. Based on the available information in the literature, it is suggested that use of PAs as drugs is very promising; however more research and clinical trials are necessary before these bioactive molecules can be made for treatment. Finally this review provides greater awareness of the promise that natural PAs hold for use in the disease prevention and therapy.http://dx.doi.org/10.1155/2015/823539
spellingShingle Venkata Saibabu
Zeeshan Fatima
Luqman Ahmad Khan
Saif Hameed
Therapeutic Potential of Dietary Phenolic Acids
Advances in Pharmacological Sciences
title Therapeutic Potential of Dietary Phenolic Acids
title_full Therapeutic Potential of Dietary Phenolic Acids
title_fullStr Therapeutic Potential of Dietary Phenolic Acids
title_full_unstemmed Therapeutic Potential of Dietary Phenolic Acids
title_short Therapeutic Potential of Dietary Phenolic Acids
title_sort therapeutic potential of dietary phenolic acids
url http://dx.doi.org/10.1155/2015/823539
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