Lung Sarcoidosis in Etanercept Treated Rheumatoid Arthritis Patient: A Case Report and Review of the Literature
We report a 55-year-old female with seropositive rheumatoid arthritis for 10 years who developed large mediastinal and hilar adenopathy while receiving etanercept therapy. Chest high resolution computed tomography (HRCT) showed mediastinal lymph nodes with size of 2.3×3.1 centimeters. Right paratrac...
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Format: | Article |
Language: | English |
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Wiley
2014-01-01
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Series: | Case Reports in Rheumatology |
Online Access: | http://dx.doi.org/10.1155/2014/358567 |
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author | Supat Thongpooswan Adriana Abrudescu |
author_facet | Supat Thongpooswan Adriana Abrudescu |
author_sort | Supat Thongpooswan |
collection | DOAJ |
description | We report a 55-year-old female with seropositive rheumatoid arthritis for 10 years who developed large mediastinal and hilar adenopathy while receiving etanercept therapy. Chest high resolution computed tomography (HRCT) showed mediastinal lymph nodes with size of 2.3×3.1 centimeters. Right paratracheal lymph node biopsy showed nonnecrotizing epithelioid granulomata. All infectious studies of pulmonary lymph node tissues were negative. Etanercept was discontinued. Follow-up HRCT 6 months later showed resolution of mediastinal lymph nodes. This report should increase awareness of pulmonary sarcoidosis development in patient treated with tumor necrosis factor-alpha blocking agent, etanercept. |
format | Article |
id | doaj-art-e1ea4a65a3274100875c533c3420deeb |
institution | Kabale University |
issn | 2090-6889 2090-6897 |
language | English |
publishDate | 2014-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Rheumatology |
spelling | doaj-art-e1ea4a65a3274100875c533c3420deeb2025-02-03T01:10:31ZengWileyCase Reports in Rheumatology2090-68892090-68972014-01-01201410.1155/2014/358567358567Lung Sarcoidosis in Etanercept Treated Rheumatoid Arthritis Patient: A Case Report and Review of the LiteratureSupat Thongpooswan0Adriana Abrudescu1Mount Sinai School of Medicine, Queens Hospital Center, Jamaica, NY 11432, USAMount Sinai School of Medicine, Queens Hospital Center, Jamaica, NY 11432, USAWe report a 55-year-old female with seropositive rheumatoid arthritis for 10 years who developed large mediastinal and hilar adenopathy while receiving etanercept therapy. Chest high resolution computed tomography (HRCT) showed mediastinal lymph nodes with size of 2.3×3.1 centimeters. Right paratracheal lymph node biopsy showed nonnecrotizing epithelioid granulomata. All infectious studies of pulmonary lymph node tissues were negative. Etanercept was discontinued. Follow-up HRCT 6 months later showed resolution of mediastinal lymph nodes. This report should increase awareness of pulmonary sarcoidosis development in patient treated with tumor necrosis factor-alpha blocking agent, etanercept.http://dx.doi.org/10.1155/2014/358567 |
spellingShingle | Supat Thongpooswan Adriana Abrudescu Lung Sarcoidosis in Etanercept Treated Rheumatoid Arthritis Patient: A Case Report and Review of the Literature Case Reports in Rheumatology |
title | Lung Sarcoidosis in Etanercept Treated Rheumatoid Arthritis Patient: A Case Report and Review of the Literature |
title_full | Lung Sarcoidosis in Etanercept Treated Rheumatoid Arthritis Patient: A Case Report and Review of the Literature |
title_fullStr | Lung Sarcoidosis in Etanercept Treated Rheumatoid Arthritis Patient: A Case Report and Review of the Literature |
title_full_unstemmed | Lung Sarcoidosis in Etanercept Treated Rheumatoid Arthritis Patient: A Case Report and Review of the Literature |
title_short | Lung Sarcoidosis in Etanercept Treated Rheumatoid Arthritis Patient: A Case Report and Review of the Literature |
title_sort | lung sarcoidosis in etanercept treated rheumatoid arthritis patient a case report and review of the literature |
url | http://dx.doi.org/10.1155/2014/358567 |
work_keys_str_mv | AT supatthongpooswan lungsarcoidosisinetanercepttreatedrheumatoidarthritispatientacasereportandreviewoftheliterature AT adrianaabrudescu lungsarcoidosisinetanercepttreatedrheumatoidarthritispatientacasereportandreviewoftheliterature |