Antibacterial polymeric nanocomposites synthesized by in-situ photoreduction of silver ions without additives inside biocompatible hydrogel matrices based on N-isopropylacrylamide and derivatives
Synthesis of antibacterial nanocomposite obtained by in-situ photoreduction of Ag+ ions impregnated inside a biocompatible hydrogel matrix is described. Hydrogel matrixes based on N-isopropylacrylamide (PNIPAM) and copolymers are synthesized by free radical polymerization in aqueous medium. The hydr...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Budapest University of Technology and Economics
2017-12-01
|
| Series: | eXPRESS Polymer Letters |
| Subjects: | |
| Online Access: | http://www.expresspolymlett.com/letolt.php?file=EPL-0008288&mi=cd |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849697704167342080 |
|---|---|
| author | M. Monerris M. Broglia I. Yslas C. Barbero C. Rivarola |
| author_facet | M. Monerris M. Broglia I. Yslas C. Barbero C. Rivarola |
| author_sort | M. Monerris |
| collection | DOAJ |
| description | Synthesis of antibacterial nanocomposite obtained by in-situ photoreduction of Ag+ ions impregnated inside a biocompatible hydrogel matrix is described. Hydrogel matrixes based on N-isopropylacrylamide (PNIPAM) and copolymers are synthesized by free radical polymerization in aqueous medium. The hydrogels are loaded with Ag+ ions and then silver nanoparticles (Ag-NPs) are obtained in-situ by application of UV light without using additives. Ag-NPs formation inside hydrogels is confirmed by UV–visible spectroscopy, scanning electronic microscopy (SEM) and transmission electronic microscopy (TEM). An extensive characterization of nanocomposites is performed by determining the partition coefficient of Ag+ ions before photoreduction, the Ag-NPs mass loaded per gram of hydrogel as a function of irradiation time, swelling capacity and volume phase transition temperature. Fourier Transform Infrared (FTIR) spectra indicate the loss of some functional groups of the polymer backbone during reduction of Ag+ ions whereas 13C NMR spectra do not show any change in the main carbon chain. Nanocomposites show antibacterial activity against Pseudomonas aeruginosas by release of Ag+ ions while Ag-NPs remain inside matrix. Reducing/stabilizing character of hydrogel and antibacterial activity of nanocomposite depend on the chemical composition of the matrix. |
| format | Article |
| id | doaj-art-e1e2fc2ff7c54ef7a0b3c43597b1b0b8 |
| institution | DOAJ |
| issn | 1788-618X |
| language | English |
| publishDate | 2017-12-01 |
| publisher | Budapest University of Technology and Economics |
| record_format | Article |
| series | eXPRESS Polymer Letters |
| spelling | doaj-art-e1e2fc2ff7c54ef7a0b3c43597b1b0b82025-08-20T03:19:07ZengBudapest University of Technology and EconomicseXPRESS Polymer Letters1788-618X2017-12-01111294696210.3144/expresspolymlett.2017.91Antibacterial polymeric nanocomposites synthesized by in-situ photoreduction of silver ions without additives inside biocompatible hydrogel matrices based on N-isopropylacrylamide and derivativesM. MonerrisM. BrogliaI. YslasC. BarberoC. RivarolaSynthesis of antibacterial nanocomposite obtained by in-situ photoreduction of Ag+ ions impregnated inside a biocompatible hydrogel matrix is described. Hydrogel matrixes based on N-isopropylacrylamide (PNIPAM) and copolymers are synthesized by free radical polymerization in aqueous medium. The hydrogels are loaded with Ag+ ions and then silver nanoparticles (Ag-NPs) are obtained in-situ by application of UV light without using additives. Ag-NPs formation inside hydrogels is confirmed by UV–visible spectroscopy, scanning electronic microscopy (SEM) and transmission electronic microscopy (TEM). An extensive characterization of nanocomposites is performed by determining the partition coefficient of Ag+ ions before photoreduction, the Ag-NPs mass loaded per gram of hydrogel as a function of irradiation time, swelling capacity and volume phase transition temperature. Fourier Transform Infrared (FTIR) spectra indicate the loss of some functional groups of the polymer backbone during reduction of Ag+ ions whereas 13C NMR spectra do not show any change in the main carbon chain. Nanocomposites show antibacterial activity against Pseudomonas aeruginosas by release of Ag+ ions while Ag-NPs remain inside matrix. Reducing/stabilizing character of hydrogel and antibacterial activity of nanocomposite depend on the chemical composition of the matrix.http://www.expresspolymlett.com/letolt.php?file=EPL-0008288&mi=cdNanocompositesReductant/stabilizer hydrogelSilver nanoparticlesPhotoreductionAntibacterial capacity |
| spellingShingle | M. Monerris M. Broglia I. Yslas C. Barbero C. Rivarola Antibacterial polymeric nanocomposites synthesized by in-situ photoreduction of silver ions without additives inside biocompatible hydrogel matrices based on N-isopropylacrylamide and derivatives eXPRESS Polymer Letters Nanocomposites Reductant/stabilizer hydrogel Silver nanoparticles Photoreduction Antibacterial capacity |
| title | Antibacterial polymeric nanocomposites synthesized by in-situ photoreduction of silver ions without additives inside biocompatible hydrogel matrices based on N-isopropylacrylamide and derivatives |
| title_full | Antibacterial polymeric nanocomposites synthesized by in-situ photoreduction of silver ions without additives inside biocompatible hydrogel matrices based on N-isopropylacrylamide and derivatives |
| title_fullStr | Antibacterial polymeric nanocomposites synthesized by in-situ photoreduction of silver ions without additives inside biocompatible hydrogel matrices based on N-isopropylacrylamide and derivatives |
| title_full_unstemmed | Antibacterial polymeric nanocomposites synthesized by in-situ photoreduction of silver ions without additives inside biocompatible hydrogel matrices based on N-isopropylacrylamide and derivatives |
| title_short | Antibacterial polymeric nanocomposites synthesized by in-situ photoreduction of silver ions without additives inside biocompatible hydrogel matrices based on N-isopropylacrylamide and derivatives |
| title_sort | antibacterial polymeric nanocomposites synthesized by in situ photoreduction of silver ions without additives inside biocompatible hydrogel matrices based on n isopropylacrylamide and derivatives |
| topic | Nanocomposites Reductant/stabilizer hydrogel Silver nanoparticles Photoreduction Antibacterial capacity |
| url | http://www.expresspolymlett.com/letolt.php?file=EPL-0008288&mi=cd |
| work_keys_str_mv | AT mmonerris antibacterialpolymericnanocompositessynthesizedbyinsituphotoreductionofsilverionswithoutadditivesinsidebiocompatiblehydrogelmatricesbasedonnisopropylacrylamideandderivatives AT mbroglia antibacterialpolymericnanocompositessynthesizedbyinsituphotoreductionofsilverionswithoutadditivesinsidebiocompatiblehydrogelmatricesbasedonnisopropylacrylamideandderivatives AT iyslas antibacterialpolymericnanocompositessynthesizedbyinsituphotoreductionofsilverionswithoutadditivesinsidebiocompatiblehydrogelmatricesbasedonnisopropylacrylamideandderivatives AT cbarbero antibacterialpolymericnanocompositessynthesizedbyinsituphotoreductionofsilverionswithoutadditivesinsidebiocompatiblehydrogelmatricesbasedonnisopropylacrylamideandderivatives AT crivarola antibacterialpolymericnanocompositessynthesizedbyinsituphotoreductionofsilverionswithoutadditivesinsidebiocompatiblehydrogelmatricesbasedonnisopropylacrylamideandderivatives |