Integrated multi-omics analysis of metabolome and transcriptome profiles during bovine adipocyte differentiation reveals functional divergence of FADS2 isoforms in lipid metabolism regulation

Integrated multi-omics analysis of metabolome and transcriptome profiles during bovine adipocyte differentiation reveals functional divergence of FADS2 isoforms in lipid metabolism regulation

Abstract Background Fat metabolism plays an important role in animal health and economic benefits. However, the changes in gene expression and metabolites during fat metabolism have not been systematically studied in bovine. Results This study integrates transcriptomic and metabolomic strategies to...

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Bibliographic Details
Main Authors: Xiaolian Zhang, Fan Li, Lingwei Peng, Wei Huang, Yuqin Du, Liguo Yang, Yang Zhou
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Genomics
Subjects:
Bovine adipocytes
Metabolite
Transcriptome
FADS2
Isoforms
Unsaturated fatty acids
Online Access:https://doi.org/10.1186/s12864-025-11650-6
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